SCHEMBL456813

SCHEMBL456813

CC1(C)CC(C)(C)OB(B2OC(C)(C)CC(C)(C)O2)O1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6238330 0.79
SCHEMBL10282974 0.76
SCHEMBL14501651 0.74
SCHEMBL13448052 0.74
SCHEMBL24215486 0.69
SCHEMBL19421251 0.69
SCHEMBL24474695 0.67
SCHEMBL6239344 0.67
SCHEMBL18056974 0.67 ANPEP (0.32)
SCHEMBL18400901 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3303288-B1 PROCESS FOR PREPARING CARBAZOLES DOW GLOBAL TECHNOLOGIES LLC (US) 2021-01-20 EP claimed
US-20020052522-A1 Boronic compounds COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION 2002-05-02 US claimed
US-6346639-B1 Boronic compounds THE COMMONWEALTH OF AUSTRALIA COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANIZATION (AU) 2002-02-12 US claimed
WO-2023220180-A1 METHODS OF MANUFACTURING PYRIDAZINONE COMPOUNDS EDGEWISE THERAPEUTICS, INC. (US) 2023-11-16 WO disclosed
US-11345665-B2 Chiral 1,3-diarylimidazolium salt carbene precursor, synthesis method therefor, metal salt compound and application thereof SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) 2022-05-31 US disclosed
US-11345665-B2 Chiral 1,3-diarylimidazolium salt carbene precursor, synthesis method therefor, metal salt compound and application thereof SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) 2022-05-31 US disclosed
CN-109680342-B Method for reducing On-DNA aromatic nitro compound in DNA coding compound library into On-DNA aromatic amine compound 上海药明康德新药开发有限公司 2021-09-28 CN disclosed
EP-3303288-B1 PROCESS FOR PREPARING CARBAZOLES DOW GLOBAL TECHNOLOGIES LLC (US) 2021-01-20 EP disclosed
US-20200369620-A1 CHIRAL 1,3-DIARYLIMIDAZOLIUM SALT CARBENE PRECURSOR, SYNTHESIS METHOD THEREFOR, METAL SALT COMPOUND AND APPLICATION THEREOF SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) 2020-11-26 US disclosed
US-10246415-B2 Process for preparing carbazoles DOW GLOBAL TECHNOLOGIES LLC (US) 2019-04-02 US disclosed
US-10166533-B2 Methods for producing borylated arenes DOW AGROSCIENCES LLC (US) 2019-01-01 US disclosed
EP-2300437-A1 BENZPYRAZOL DERIVATIVES AS INHIBITORS OF PI3 KINASES Glaxo Group Limited (GB) 2011-03-30 EP disclosed
EP-2280946-A1 4-CARBOXAMIDE INDAZOLE DERIVATIVES USEFUL AS INHIBITORS OF P13-KINASES Glaxo Group Limited (GB) 2011-02-09 EP disclosed
WO-2010102958-A1 4-OXADIAZOL-2 -YL- INDAZOLES AS INHIBITORS OF P13 KINASES GLAXO GROUP LIMITED (GB) 2010-09-16 WO disclosed
WO-2009147187-A1 4-CARBOXAMIDE INDAZOLE DERIVATIVES USEFUL AS INHIBITORS OF P13-KINASES GLAXO GROUP LIMITED (GB) 2009-12-10 WO disclosed
WO-2009147188-A1 BENZPYRAZOL DERIVATIVES AS INHIBITORS OF PI3 KINASES GLAXO GROUP LIMITED (GB) 2009-12-10 WO disclosed
EP-1121365-B1 ORGANOBORON DERIVATIVES AND PROCESS FOR COUPLING ORGANIC COMPOUNDS COMMW SCIENT IND RES ORG (AU) 2005-06-08 EP disclosed
US-6515160-B2 Boronic compounds COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2003-02-04 US disclosed
US-20020052522-A1 Boronic compounds COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION 2002-05-02 US disclosed
US-6346639-B1 Boronic compounds THE COMMONWEALTH OF AUSTRALIA COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANIZATION (AU) 2002-02-12 US disclosed