Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 4/20 | 0.45 |
| ▸ | F10 | P00742 | 11/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | F11 | P03951 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3088969 | 0.92 | MIF (0.46) | MIFF10HPGDF2F11 | |
| SCHEMBL3100876 | 0.89 | MIF (0.49) | MIFF10HPGDF2APP | |
| SCHEMBL3091712 | 0.88 | MIF (0.47) | MIFF10HPGDF2P2RX7 | |
| SCHEMBL14147682 | 0.88 | MIF (0.47) | MIFF10HPGDP2RX7 | |
| SCHEMBL3082940 | 0.87 | MIF (0.47) | MIFF10HPGDAPP | |
| SCHEMBL3091408 | 0.87 | MIF (0.47) | MIFF10HPGDF2F11 | |
| SCHEMBL1096208 | 0.86 | MIF (0.52) | MIFF10HPGDAPP | |
| SCHEMBL3081555 | 0.86 | MIF (0.45) | MIFF10HPGDF2F11 | |
| SCHEMBL3086389 | 0.86 | MIF (0.45) | MIFF10HPGDP2RX7APP | |
| SCHEMBL3097969 | 0.84 | MIF (0.44) | MIFF10HPGDAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2114928-A2 | THIOPHENE CARBOXAMIDES AS FACTOR XA INHIBITORS | Millennium Pharmaceuticals, Inc. (US) | 2009-11-11 | — | — | EP | claimed |
| WO-2008086188-A2 | THIOPHENE CARBOXAMIDES AS FACTOR XA INHIBITORS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2008-07-17 | — | — | WO | claimed |