Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3240613 | 0.92 | HRH3 (0.64) | HRH3CYP2D6 | |
| SCHEMBL3241082 | 0.92 | HRH3 (0.64) | HRH3CYP2D6 | |
| SCHEMBL3248147 | 0.92 | HRH3 (0.66) | HRH3CYP2D6 | |
| SCHEMBL3248151 | 0.90 | HRH3 (0.62) | HRH3CYP2D6 | |
| SCHEMBL3249417 | 0.90 | HRH3 (0.64) | HRH3CYP2D6 | |
| Hydrochloric Acid SCHEMBL3243366 | 0.90 | HRH3 (0.64) | HRH3CYP2D6 | |
| SCHEMBL3247580 | 0.90 | HRH3 (0.62) | HRH3CYP2D6 | |
| SCHEMBL3248515 | 0.90 | HRH3 (0.62) | HRH3CYP2D6 | |
| SCHEMBL3254225 | 0.90 | HRH3 (0.64) | HRH3CYP2D6 | |
| SCHEMBL3240654 | 0.88 | HRH3 (0.60) | HRH3CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2118089-A1 | INDOL-2-YL-PIPERAZIN-1-YL-METHANONE DERIVATIVES | F. Hoffmann-Roche AG (CH) | 2009-11-18 | — | — | EP | disclosed |
| WO-2008095821-A1 | INDOL-2-YL-PIPERAZIN-1-YL-METHANONE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2008-08-14 | — | — | WO | disclosed |