SCHEMBL457230

SCHEMBL457230

Cc1c(Br)[c]ccc1Br

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL773688 0.84
SCHEMBL1030817 0.79
SCHEMBL29262467 0.75
SCHEMBL28399893 0.75
SCHEMBL28552386 0.75
SCHEMBL456135 0.74
SCHEMBL147747 0.72
SCHEMBL28582611 0.72 CA12 (0.33)
SCHEMBL8313811 0.70
SCHEMBL25302090 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112469412-A Substituted dihydropyrazolopyrazine carboxamide derivatives 拜耳公司 2021-03-09 CN disclosed
EP-3045450-B1 INTERMEDIATE COMPOUNDS IN PROCESSES FOR PRODUCING PYRIDAZINONE COMPOUNDS SUMITOMO CHEMICAL CO (JP) 2018-02-07 EP disclosed
EP-3045450-A1 INTERMEDIATE COMPOUNDS IN A PROCESS FOR PRODUCING PYRIDAZINONE COMPOUNDS SUMITOMO CHEMICAL CO., LTD. (JP) 2016-07-20 EP disclosed
EP-2614053-B1 METHOD FOR PRODUCING PYRIDAZINONE COMPOUNDS AND INTERMEDIATES THEREOF SUMITOMO CHEMICAL CO (JP) 2016-03-23 EP disclosed
US-9040709-B2 Method for producing pyridazinone compounds and intermediate thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-05-26 US disclosed
US-20140378688-A1 METHOD FOR PRODUCING PYRIDAZINONE COMPOUNDS AND INTERMEDIATE THEREOF SUMITOMO CHEMICAL CO (JP) 2014-12-25 US disclosed
US-8884010-B2 Method for producing pyridazinone compounds and intermediate thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-11-11 US disclosed
EP-2614053-A1 METHOD FOR PRODUCING PYRIDAZINONE COMPOUNDS AND INTERMEDIATE THEREOF SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2013-07-17 EP disclosed
US-20130172556-A1 METHOD FOR PRODUCING PYRIDAZINONE COMPOUNDS AND INTERMEDIATE THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-07-04 US disclosed
CN-103189371-A Novel hepatitis c virus inhibitors THERAVANCE INC 2013-07-03 CN disclosed
WO-2012033225-A1 METHOD FOR PRODUCING PYRIDAZINONE COMPOUNDS AND INTERMEDIATE THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-03-15 WO disclosed
US-20090030248-A1 Ethynylphenylbiadamantane derivatives DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2009-01-29 US disclosed
EP-2014636-A1 Ethynylphenylbiadamantane derivatives Daicel Chemical Industries, Ltd. (JP) 2009-01-14 EP disclosed
EP-0724586-B1 PROCESS FOR PREPARING N-(2,6-DICHLORO-3-METHYLPHENYL)-5-7-DIHALO[1,2,4]TRIAZOLO[1,5A]PYRIMIDINE-2-SULFONAMIDE BY CYCLIZATION AND HALO-DEHYDROXYLATION DOW AGROSCIENCES LLC (US) 2002-01-23 EP disclosed
EP-0724586-A1 PROCESS FOR PREPARING N-(2,6-DICHLORO-3-METHYLPHENYL)-5-7-DIHALO 1,2,4]TRIAZOLO 1,5A]PYRIMIDINE-2-SULFONAMIDE BY CYCLIZATION AND HALO-DEHYDROXYLATION DOWELANCO (US) 1996-08-07 EP disclosed
WO-1995011246-A1 PROCESS FOR PREPARING N-(2,6-DICHLORO-3-METHYLPHENYL)-5-7-DIHALO[1,2,4]TRIAZOLO[1,5A]PYRIMIDINE-2-SULFONAMIDE BY CYCLIZATION AND HALO-DEHYDROXYLATION DOWELANCO (US) 1995-04-27 WO disclosed