Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 16/20 | 0.64 |
| ▸ | HSP90AB1 | P08238 | 13/20 | 0.60 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.50 |
| ▸ | TRAP1 | Q12931 | 1/20 | 0.50 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.47 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.47 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.47 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14193524 | 1.00 | HSP90AA1 (0.64) | HSP90AA1HSP90AB1HSP90B1TRAP1PDK1 | |
| SCHEMBL14194413 | 0.86 | HSP90AA1 (0.63) | HSP90AA1HSP90AB1 | |
| SCHEMBL14194418 | 0.82 | HSP90AA1 (0.64) | HSP90AA1HSP90AB1 | |
| SCHEMBL384744 | 0.79 | HSP90AA1 (0.82) | HSP90AA1HSP90AB1HSP90B1TRAP1 | |
| SCHEMBL14193538 | 0.75 | HSP90AA1 (0.55) | HSP90AA1HSP90AB1 | |
| SCHEMBL4573078 | 0.75 | HSP90AA1 (1.00) | HSP90AA1HSP90AB1 | |
| SCHEMBL14194419 | 0.75 | HSP90AA1 (1.00) | HSP90AA1HSP90AB1 | |
| SCHEMBL14194412 | 0.75 | HSP90AA1 (1.00) | HSP90AA1HSP90AB1 | |
| SCHEMBL14193539 | 0.72 | HSP90AA1 (0.49) | HSP90AA1HSP90AB1 | |
| SCHEMBL14193541 | 0.71 | HSP90AA1 (0.56) | HSP90AA1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008053319-A1 | AMIDE RESORCINOL COMPOUNDS | PFIZER PRODUCTS INC. (US) | 2008-05-08 | — | — | WO | disclosed |