Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 18/20 | 0.58 |
| ▸ | HCRTR2 | O43614 | 18/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4573689 | 1.00 | HCRTR1 (0.58) | HCRTR1HCRTR2MEN1KMT2A | |
| SCHEMBL3682511 | 0.92 | HCRTR2 (0.54) | HCRTR1HCRTR2MEN1KMT2A | |
| SCHEMBL6455357 | 0.92 | HCRTR2 (0.54) | HCRTR1HCRTR2MEN1KMT2A | |
| SCHEMBL4573105 | 0.82 | HCRTR1 (0.56) | HCRTR1HCRTR2KMT2A | |
| SCHEMBL4573101 | 0.82 | HCRTR1 (0.56) | HCRTR1HCRTR2KMT2A | |
| SCHEMBL8366845 | 0.81 | HCRTR1 (0.64) | HCRTR1HCRTR2 | |
| SCHEMBL1965055 | 0.81 | HCRTR1 (0.64) | HCRTR1HCRTR2 | |
| SCHEMBL4574022 | 0.80 | HCRTR1 (0.57) | HCRTR1HCRTR2 | |
| SCHEMBL4574026 | 0.80 | HCRTR1 (0.57) | HCRTR1HCRTR2 | |
| SCHEMBL19382661 | 0.80 | HCRTR1 (0.62) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008031788-A1 | AMINOAZEPINE DERIVATIVES AS HIGHLY EFFICIENT INHIBITORS OF THE INDUCIBLE NITRIC OXIDE SYNTHASE | NYCOMED GMBH (DE) | 2008-03-20 | — | — | WO | disclosed |
| WO-2008031788-A1 | AMINOAZEPINE DERIVATIVES AS HIGHLY EFFICIENT INHIBITORS OF THE INDUCIBLE NITRIC OXIDE SYNTHASE | NYCOMED GMBH (DE) | 2008-03-20 | — | — | WO | disclosed |