Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 8/20 | 0.71 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.71 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.71 |
| ▸ | HTR1A | P08908 | 2/20 | 0.70 |
| ▸ | MLNR | O43193 | 1/20 | 0.70 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.70 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.70 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.70 |
| ▸ | GAA | P10253 | 1/20 | 0.70 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.70 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.70 |
| ▸ | DRD2 | P14416 | 1/20 | 0.70 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.70 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.70 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.70 |
| ▸ | HTR2A | P28223 | 1/20 | 0.70 |
| ▸ | HTR2C | P28335 | 1/20 | 0.70 |
| ▸ | MC4R | P32245 | 1/20 | 0.70 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4573568 | 1.00 | SLC6A2 (0.71) | SLC6A2SLC6A4SLC6A3HTR1AMLNR | |
| Methylamine SCHEMBL27678263 | 0.97 | SLC6A2 (0.72) | SLC6A2SLC6A4SLC6A3HTR1AMLNR | |
| Dimethylamine SCHEMBL2107318 | 0.96 | SLC6A2 (0.73) | SLC6A2SLC6A4SLC6A3HTR1AMLNR | |
| Methylamine SCHEMBL19379630 | 0.96 | SLC6A2 (0.70) | SLC6A2SLC6A4SLC6A3HTR1AMLNR | |
| Methylhydrazine SCHEMBL27734680 | 0.94 | SLC6A2 (0.70) | SLC6A2SLC6A4SLC6A3HTR1AMLNR | |
| SCHEMBL12212180 | 0.89 | SLC6A2 (0.76) | SLC6A2SLC6A4SLC6A3HTR1AMLNR | |
| N-Benzylmethylamine SCHEMBL27970819 | 0.88 | SLC6A2 (0.67) | SLC6A2SLC6A4SLC6A3HTR1AMLNR | |
| SCHEMBL2738887 | 0.85 | SLC6A2 (0.77) | SLC6A2SLC6A4SLC6A3HTR1AMLNR | |
| SCHEMBL13689324 | 0.85 | SLC6A2 (0.67) | SLC6A2SLC6A4SLC6A3HTR1AMLNR | |
| SCHEMBL27847200 | 0.84 | SLC6A2 (0.82) | SLC6A2SLC6A4SLC6A3HTR1AMLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008081476-A2 | PROCESS FOR PREPARING DULOXETINE HYDROCHLORIDE | CADILA HEALTHCARE LIMITED (IN) | 2008-07-10 | — | — | WO | claimed |
| WO-2008081476-A2 | PROCESS FOR PREPARING DULOXETINE HYDROCHLORIDE | CADILA HEALTHCARE LIMITED (IN) | 2008-07-10 | — | — | WO | disclosed |