SCHEMBL4573899

SCHEMBL4573899

CCCCCCCNC(=O)C1CSC(c2ccccc2)N1

nearest known ligand 0.59

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
S1PR3 Q99500 2/20 0.59
ALDH1A1 P00352 6/20 0.50
PRCP P42785 2/20 0.49
KDM4E B2RXH2 3/20 0.47
MAPT P10636 2/20 0.47
NAAA Q02083 1/20 0.47
EPHX1 P07099 3/20 0.45
HTT P42858 1/20 0.45
HSD17B10 Q99714 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5392579 1.00 S1PR3 (0.59) S1PR3ALDH1A1PRCPKDM4EMAPT
SCHEMBL29776727 1.00 S1PR3 (0.59) S1PR3ALDH1A1PRCPKDM4EMAPT
SCHEMBL4421784 1.00 S1PR3 (0.59) S1PR3ALDH1A1PRCPKDM4EMAPT
SCHEMBL3557711 1.00 S1PR3 (0.59) S1PR3ALDH1A1PRCPKDM4EMAPT
SCHEMBL4573866 1.00 S1PR3 (0.59) S1PR3ALDH1A1PRCPKDM4EMAPT
SCHEMBL4751119 1.00 S1PR3 (0.59) S1PR3ALDH1A1PRCPKDM4EMAPT
SCHEMBL3553011 1.00 S1PR3 (0.59) S1PR3ALDH1A1PRCPKDM4EMAPT
SCHEMBL3553095 1.00 S1PR3 (0.59) S1PR3ALDH1A1PRCPKDM4EMAPT
SCHEMBL3555702 1.00 S1PR3 (0.59) S1PR3ALDH1A1PRCPKDM4EMAPT
Hydrochloric Acid SCHEMBL4574538 0.99 S1PR3 (0.58) S1PR3ALDH1A1PRCPKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008128179-A1 THIAZOLIDINONE AMIDES, THIAZOLIDINE CARBOXYLIC ACID AMIDES, AND SERINE AMIDES, INCLUDING POLYAMINE CONJUGATES THEREOF, AS SELECTIVE ANTI-CANCER AGENTS THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2008-10-23 WO disclosed
EP-1926487-A2 THIAZOLIDINONE AMIDES, THIAZOLIDINE CARBOXYLIC ACID AMIDES, AND SERINE AMIDES, INCLUDING POLYAMINE CONJUGATES THEREOF, AS SELECTIVE ANTI-CANCER AGENTS University of Tennessee Research Foundation (US) 2008-06-04 EP disclosed
WO-2008036067-A2 THIAZOLIDINONE AMIDES, THIAZOLIDINE CARBOXYLIC ACID AMIDES, AND SERINE AMIDES, INCLUDING POLYAMINE CONJUGATES THEREOF, AS SELECTIVE ANTI-CANCER AGENTS THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2008-03-27 WO disclosed
EP-1692121-A1 THIAZOLIDINONE AMIDES, THIAZOLIDINE CARBOXYLIC ACID AMIDES, METHODS OF MAKING, AND USES THEREOF University of Tennessee Research Foundation (US) 2006-08-23 EP disclosed
WO-2005049591-A1 THIAZOLIDINONE AMIDES, THIAZOLIDINE CARBOXYLIC ACID AMIDES, METHODS OF MAKING, AND USES THEREOF UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2005-06-02 WO disclosed