SCHEMBL4574

SCHEMBL4574

c1ccc(C2CCNCC2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SLC18A3 Q16572 2/20 1.00
SIGMAR1 Q99720 1/20 1.00
HTR2C P28335 10/20 0.59
HPGD P15428 1/20 0.58
KMT2A Q03164 1/20 0.58
SMN1; SMN2 Q16637 1/20 0.58
HTR6 P50406 1/20 0.51
QDPR P09417 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL28128069 1.00 SLC18A3 (1.00) SLC18A3SIGMAR1HTR2CHPGDKMT2A
Hydrogen Sulfide SCHEMBL27710844 0.98 SLC18A3 (0.95) SLC18A3SIGMAR1HTR2CHPGDKMT2A
Hydrochloric Acid SCHEMBL1481633 0.98 SLC18A3 (0.95) SLC18A3SIGMAR1HTR2CHPGDKMT2A
Piperazine SCHEMBL27350525 0.98 SLC18A3 (0.95) SLC18A3SIGMAR1HTR2CHPGDKMT2A
Hydrochloric Acid SCHEMBL27731257 0.95 SLC18A3 (0.91) SLC18A3SIGMAR1HTR2CHPGDKMT2A
Hydrochloric Acid SCHEMBL27646918 0.95 SLC18A3 (0.91) SLC18A3SIGMAR1HTR2CHPGDKMT2A
Pyrrolidine SCHEMBL28789780 0.93 SLC18A3 (0.87) SLC18A3SIGMAR1HTR2CHPGDKMT2A
SCHEMBL23638807 0.91 SLC18A3 (0.83) SLC18A3SIGMAR1HTR2CHPGDKMT2A
SCHEMBL2300489 0.91 SLC18A3 (0.83) SLC18A3SIGMAR1HTR2CHPGDKMT2A
Hydrochloric Acid SCHEMBL2264294 0.89 SLC18A3 (0.80) SLC18A3SIGMAR1HTR2CHPGDKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4938 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122036599-A Dibenzylbutane lignan LCA analogue, and preparation method and application thereof 浙江中医药大学 2026-05-15 CN claimed
US-12570632-B2 Indole derivatives and uses thereof for treating a cancer UNIVERSITE CLAUDE BERNARD LYON 1 (FR) 2026-03-10 US claimed
US-20260022096-A1 NOVEL SULFONAMIDES AND THEIR USE AS NEUROPROTECTIVE AND/OR NEURORESTORATIVE AGENTS GENECODE (EE) 2026-01-22 US claimed
WO-2025224749-A1 ADDITIVE/CATALYST FREE AMINOLYSIS FOR DEPOLYMERIZATION OF REAL-LIFE POLYCARBONATES TO VALUE ADDED PRODUCTS COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2025-10-30 WO claimed
US-20250277131-A1 MULTI-AMINE POLYESTER DISPERSANT MADE VIA AN ANHYDRIDE INTERMEDIATE LUBRIZOL ADVANCED MATERIALS, INC. (US) 2025-09-04 US claimed
US-12338361-B2 Multi-amine polyester dispersant made via an anhydride intermediate LUBRIZOL ADVANCED MATERIALS, INC. (US) 2025-06-24 US claimed
CN-120117949-A Method for directly preparing tertiary amine compound from aromatic aldehyde, ketone and secondary amine 湖南大学 2025-06-10 CN claimed
EP-4561994-A1 NOVEL SULFONAMIDES AND THEIR USE AS NEUROPROTECTIVE AND/OR NEURORESTORATIVE AGENTS Genecode (EE) 2025-06-04 EP claimed
CN-116768826-B Rupestonic acid amide derivative containing nitrogen heterocycle, and preparation method and application thereof 中国科学院新疆理化技术研究所 2025-05-27 CN claimed
CN-120035580-A Novel piperazinyl sulfonamides and their use as neuroprotective and/or neurorestorative agents 基因密码公司 2025-05-23 CN claimed
US-4412994-A AMINE COMPOUNDS CONTAINING THE ACYL RESIDUE OF INDOMETHACIN AS A SUBSTITUENT INTERX RESEARCH CORPORATION (US) 1983-11-01 US claimed
EP-0023569-B1 DERIVATIVES OF CARBOXYLIC ACIDS, THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM Dr. Karl Thomae GmbH (DE) 1983-06-22 EP claimed
EP-0051278-A1 Soft tertiary amine esters of bio-affecting carboxylic acids, processes for preparing and a pharmaceutical composition containing the same MERCK & CO. INC. (US) 1982-05-12 EP claimed
EP-0039051-A2 Mannich-base hydroxamic acid prodrugs for the improved bioavailability of non-steroidal anti-inflammatory agents, a process for preparing and a pharmaceutical composition containing them MERCK & CO. INC. (US) 1981-11-04 EP claimed
US-4286095-A CNS STIMULANTS; ANTIDEPRESSANTS, DIURETICS, AND BRONCHODILATOR AGENTS CANADA PACKERS INC. (CA) 1981-08-25 US claimed
EP-0020304-A1 Guanidines, process for their preparation, pharmaceutical preparations containing such compounds and their application CIBA-GEIGY AG (CH) 1980-12-10 EP claimed
EP-0020303-A1 Guanidines, process for their preparation, pharmaceutical preparations containing such compounds and their application CIBA-GEIGY AG (CH) 1980-12-10 EP claimed
US-4236009-A Method of preparing 4A-arylhexahydro-1H-2-pyrindines and 4A-aryloctahydroisoquinolines ELI LILLY AND COMPANY (US) 1980-11-25 US claimed
US-4139626-A FUNGICIDES SYNTEX (U.S.A.) INC. (US) 1979-02-13 US claimed
US-3983107-A ARTERIOSCLEROSIS PFIZER INC. (US) 1976-09-28 US claimed