Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.81 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.81 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.81 |
| ▸ | TST | Q16762 | 1/20 | 0.81 |
| ▸ | RECQL | P46063 | 1/20 | 0.81 |
| ▸ | BLM | P54132 | 1/20 | 0.81 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.81 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.39 |
| ▸ | PPM1A | P35813 | 2/20 | 0.39 |
| ▸ | TYR | P14679 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.33 |
| ▸ | LPAR4 | Q99677 | 1/20 | 0.33 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4394069 | 1.00 | MAPT (0.81) | MAPTHSPD1HSPE1TSTRECQL | |
| SCHEMBL4394073 | 1.00 | MAPT (0.81) | MAPTHSPD1HSPE1TSTRECQL | |
| SCHEMBL17548911 | 0.92 | MAPT (0.90) | MAPTHSPD1HSPE1TSTRECQL | |
| SCHEMBL17750096 | 0.91 | MAPT (0.97) | MAPTHSPD1HSPE1TSTRECQL | |
| SCHEMBL972299 | 0.91 | MAPT (0.97) | MAPTHSPD1HSPE1TSTRECQL | |
| SCHEMBL24511445 | 0.90 | MAPT (1.00) | MAPTHSPD1HSPE1TSTRECQL | |
| SCHEMBL8472638 | 0.90 | MAPT (1.00) | MAPTHSPD1HSPE1TSTRECQL | |
| SCHEMBL22749133 | 0.90 | MAPT (1.00) | MAPTHSPD1HSPE1TSTRECQL | |
| SCHEMBL22749146 | 0.90 | MAPT (1.00) | MAPTHSPD1HSPE1TSTRECQL | |
| SCHEMBL22749131 | 0.90 | MAPT (1.00) | MAPTHSPD1HSPE1TSTRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008080988-A2 | CYCLOPENTANONE DERIVATIVES, METHOD OF SYNTHESIS AND USES THEREOF | NEUROPHARMA, S.A. (ES) | 2008-07-10 | — | — | WO | claimed |
| EP-1939192-A1 | Cyclopentanone derivatives, method of synthesis and uses thereof | Neuropharma S.A. (ES) | 2008-07-02 | — | — | EP | claimed |
| EP-3444240-A1 | BRAIN-TARGETING PRODRUG FOR AMPA RECEPTOR SYNERGIST, AND PHARMACEUTICAL APPLICATIONS | Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China (CN) | 2019-02-20 | — | — | EP | disclosed |
| WO-2008080988-A2 | CYCLOPENTANONE DERIVATIVES, METHOD OF SYNTHESIS AND USES THEREOF | NEUROPHARMA, S.A. (ES) | 2008-07-10 | — | — | WO | disclosed |
| EP-1939192-A1 | Cyclopentanone derivatives, method of synthesis and uses thereof | Neuropharma S.A. (ES) | 2008-07-02 | — | — | EP | disclosed |