Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | RBP1 | P09455 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 5/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4574278 | 0.92 | KMT2A (0.41) | KMT2AMEN1L3MBTL1LMNAMAPT | |
| SCHEMBL4574830 | 0.89 | KMT2A (0.47) | KMT2AMEN1L3MBTL1LMNAMAPT | |
| SCHEMBL4746729 | 0.88 | KMT2A (0.40) | KMT2AMEN1L3MBTL1LMNAMAPT | |
| SCHEMBL8212341 | 0.88 | KMT2A (0.46) | KMT2AMEN1L3MBTL1LMNAMAPT | |
| SCHEMBL4574604 | 0.79 | KMT2A (0.42) | KMT2AMEN1L3MBTL1LMNAMAPT | |
| SCHEMBL4575272 | 0.78 | KMT2A (0.55) | KMT2AMEN1L3MBTL1LMNAMAPT | |
| SCHEMBL8223460 | 0.77 | RBP1 (0.40) | KMT2AMEN1L3MBTL1LMNAMAPT | |
| SCHEMBL4574917 | 0.77 | KMT2A (0.46) | KMT2AMEN1L3MBTL1LMNAMAPT | |
| SCHEMBL4574617 | 0.76 | KMT2A (0.62) | KMT2AMEN1L3MBTL1LMNAMAPT | |
| SCHEMBL4575063 | 0.75 | ALOX5AP (0.43) | KMT2AMEN1L3MBTL1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008050200-A1 | OXADIAZOLE COMPOUNDS AS CALCIUM CHANNEL ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2008-05-02 | — | — | WO | disclosed |
| WO-2008050200-A1 | OXADIAZOLE COMPOUNDS AS CALCIUM CHANNEL ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2008-05-02 | — | — | WO | disclosed |