Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 3/20 | 0.60 |
| ▸ | PRMT6 | Q96LA8 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | BCHE | P06276 | 2/20 | 0.48 |
| ▸ | ACHE | P22303 | 2/20 | 0.48 |
| ▸ | BACE1 | P56817 | 2/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
| ▸ | KDM5A | P29375 | 1/20 | 0.45 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.45 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.44 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.43 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.43 |
| ▸ | DAO | P14920 | 1/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2466378 | 0.89 | CARM1 (0.68) | CARM1PRMT6ALDH1A1BCHEACHE | |
| SCHEMBL29456931 | 0.89 | CARM1 (0.68) | CARM1PRMT6ALDH1A1BCHEACHE | |
| SCHEMBL1006996 | 0.83 | CARM1 (0.61) | CARM1PRMT6ALDH1A1BCHEACHE | |
| SCHEMBL375222 | 0.83 | CARM1 (0.61) | CARM1PRMT6ALDH1A1BCHEACHE | |
| SCHEMBL8216669 | 0.80 | CARM1 (0.61) | CARM1PRMT6ALDH1A1BCHEACHE | |
| SCHEMBL4590922 | 0.79 | CARM1 (0.57) | CARM1PRMT6ALDH1A1BCHEACHE | |
| SCHEMBL8214422 | 0.79 | CARM1 (0.54) | CARM1PRMT6ALDH1A1BCHEACHE | |
| SCHEMBL8212416 | 0.78 | CARM1 (0.56) | CARM1PRMT6ALDH1A1BCHEACHE | |
| SCHEMBL8208284 | 0.78 | CARM1 (0.59) | CARM1PRMT6ALDH1A1BCHEACHE | |
| SCHEMBL4399401 | 0.77 | CRBN (0.51) | CARM1PRMT6MAPK14KDM5AKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008065500-A2 | HETEROARYL AMIDES AS TYPE I GLYCINE TRANSPORT INHIBITORS | PFIZER PRODUCTS INC. (US) | 2008-06-05 | — | — | WO | disclosed |
| WO-2008065500-A2 | HETEROARYL AMIDES AS TYPE I GLYCINE TRANSPORT INHIBITORS | PFIZER PRODUCTS INC. (US) | 2008-06-05 | — | — | WO | disclosed |