Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 16/20 | 0.57 |
| ▸ | PPARD | Q03181 | 11/20 | 0.57 |
| ▸ | PPARG | P37231 | 11/20 | 0.57 |
| ▸ | POLQ | O75417 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4575631 | 0.91 | PPARA (0.54) | PPARAPPARDPPARGPOLQ | |
| SCHEMBL4575324 | 0.91 | PPARA (0.52) | PPARAPPARDPPARG | |
| SCHEMBL4575332 | 0.91 | PPARA (0.51) | PPARAPPARDPPARG | |
| SCHEMBL4576038 | 0.91 | PPARA (0.51) | PPARAPPARDPPARG | |
| SCHEMBL4576122 | 0.88 | PPARA (0.56) | PPARAPPARDPPARG | |
| SCHEMBL4575633 | 0.87 | PPARA (0.53) | PPARAPPARDPPARGPOLQ | |
| SCHEMBL4575388 | 0.87 | PPARG (0.73) | PPARAPPARDPPARGPOLQ | |
| SCHEMBL4575657 | 0.86 | PPARA (0.56) | PPARAPPARDPPARG | |
| SCHEMBL4575298 | 0.86 | PPARA (0.51) | PPARAPPARDPPARG | |
| SCHEMBL4574770 | 0.85 | PPARA (0.53) | PPARAPPARDPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7319104-B2 | hPPARs activators | SMITHKLINE BEECHAM CORPORATION (US) | 2008-01-15 | — | — | US | disclosed |
| US-7319104-B2 | hPPARs activators | SMITHKLINE BEECHAM CORPORATION (US) | 2008-01-15 | — | — | US | disclosed |
| US-7319104-B2 | hPPARs activators | SMITHKLINE BEECHAM CORPORATION (US) | 2008-01-15 | — | — | US | disclosed |
| EP-1480957-A1 | HPPARS ACTIVATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-12-01 | — | — | EP | disclosed |
| WO-2003074495-A1 | HPPARS ACTIVATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2003-09-12 | — | — | WO | disclosed |