Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 15/20 | 0.43 |
| ▸ | PPARD | Q03181 | 10/20 | 0.43 |
| ▸ | PPARG | P37231 | 10/20 | 0.43 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.37 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4575635 | 0.93 | PPARA (0.47) | PPARAPPARDPPARG | |
| SCHEMBL4575271 | 0.91 | PPARA (0.41) | PPARAPPARDPPARGCYP4F2CYP4A11 | |
| SCHEMBL4575364 | 0.89 | PPARG (0.42) | PPARAPPARDPPARGCYP4F2CYP4A11 | |
| SCHEMBL4575774 | 0.86 | PPARA (0.45) | PPARAPPARDPPARG | |
| SCHEMBL4575298 | 0.84 | PPARA (0.51) | PPARAPPARDPPARG | |
| SCHEMBL4575795 | 0.83 | PPARA (0.44) | PPARAPPARDPPARG | |
| SCHEMBL4575237 | 0.83 | PPARA (0.39) | PPARAPPARDPPARG | |
| SCHEMBL4575866 | 0.82 | PPARA (0.50) | PPARAPPARDPPARG | |
| SCHEMBL4575145 | 0.82 | PPARA (0.47) | PPARAPPARDPPARG | |
| SCHEMBL4575078 | 0.81 | FFAR1 (0.42) | PPARAPPARDPPARGCYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7319104-B2 | hPPARs activators | SMITHKLINE BEECHAM CORPORATION (US) | 2008-01-15 | — | — | US | disclosed |
| US-7319104-B2 | hPPARs activators | SMITHKLINE BEECHAM CORPORATION (US) | 2008-01-15 | — | — | US | disclosed |
| US-7319104-B2 | hPPARs activators | SMITHKLINE BEECHAM CORPORATION (US) | 2008-01-15 | — | — | US | disclosed |
| EP-1480957-A1 | HPPARS ACTIVATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-12-01 | — | — | EP | disclosed |
| WO-2003074495-A1 | HPPARS ACTIVATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2003-09-12 | — | — | WO | disclosed |