SCHEMBL4575397

SCHEMBL4575397

Cc1nc([N+](=O)[O-])c(C=O)[nH]1

nearest known ligand 0.38

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.32
MAPT P10636 1/20 0.32
GALR3 O60755 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL64089 0.74 MAPT (0.35) ALDH1A1MAPTGALR3
SCHEMBL8953652 0.72 MAPT (0.45) ALDH1A1MAPTGALR3
SCHEMBL948785 0.72
SCHEMBL5030585 0.71 MAPT (0.37) ALDH1A1MAPTGALR3
SCHEMBL11405724 0.71 KMT2A (0.38) ALDH1A1MAPTGALR3
SCHEMBL3676705 0.71 MAPT (0.38) ALDH1A1MAPTGALR3
SCHEMBL3641126 0.71 GALR3 (0.39) ALDH1A1MAPTGALR3
SCHEMBL4304025 0.71 SMN1; SMN2 (0.36) ALDH1A1MAPTGALR3
SCHEMBL11431900 0.71
SCHEMBL4575292 0.67 GALR3 (0.36) ALDH1A1MAPTGALR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008039087-A2 INDOLINE DERIVATIVES AND USES THEREOF AUCKLAND UNISERVICES LIMITED (NZ) 2008-04-03 WO disclosed