Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 18/20 | 0.52 |
| ▸ | PPARG | P37231 | 16/20 | 0.52 |
| ▸ | PPARD | Q03181 | 11/20 | 0.52 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4575440 | 0.94 | PPARA (0.52) | PPARAPPARGPPARD | |
| SCHEMBL4575330 | 0.91 | PPARA (0.57) | PPARAPPARGPPARD | |
| SCHEMBL14307863 | 0.91 | PPARA (0.54) | PPARAPPARGPPARD | |
| SCHEMBL4575754 | 0.88 | PPARA (0.47) | PPARAPPARGPPARDSLC22A12 | |
| SCHEMBL4574853 | 0.88 | PPARA (0.56) | PPARAPPARGPPARD | |
| SCHEMBL4575426 | 0.85 | PPARA (0.55) | PPARAPPARGPPARD | |
| SCHEMBL4574820 | 0.85 | PPARA (0.59) | PPARAPPARGPPARD | |
| SCHEMBL4575427 | 0.85 | PPARA (0.54) | PPARAPPARGPPARD | |
| SCHEMBL4575211 | 0.84 | PPARA (0.59) | PPARAPPARGPPARD | |
| SCHEMBL4575961 | 0.83 | PPARA (0.57) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7319104-B2 | hPPARs activators | SMITHKLINE BEECHAM CORPORATION (US) | 2008-01-15 | — | — | US | disclosed |
| US-7319104-B2 | hPPARs activators | SMITHKLINE BEECHAM CORPORATION (US) | 2008-01-15 | — | — | US | disclosed |