Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 14/20 | 0.43 |
| ▸ | PPARD | Q03181 | 8/20 | 0.43 |
| ▸ | PPARG | P37231 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 3/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.36 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.35 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4576139 | 1.00 | PPARA (0.43) | PPARAPPARDPPARGMEN1KMT2A | |
| SCHEMBL4575174 | 0.90 | PPARA (0.43) | PPARAPPARDPPARGMEN1KMT2A | |
| SCHEMBL4575170 | 0.90 | PPARA (0.43) | PPARAPPARDPPARGMEN1KMT2A | |
| SCHEMBL4575309 | 0.89 | PPARA (0.55) | PPARAPPARDPPARGMEN1KMT2A | |
| SCHEMBL4575313 | 0.89 | PPARA (0.55) | PPARAPPARDPPARGMEN1KMT2A | |
| SCHEMBL4575123 | 0.78 | PPARA (0.45) | PPARAPPARDPPARGMEN1KMT2A | |
| SCHEMBL4575333 | 0.73 | PPARA (0.48) | PPARAPPARDPPARGMEN1KMT2A | |
| SCHEMBL25299494 | 0.70 | PPARA (0.49) | PPARAPPARDPPARGNR1H2NR1H3 | |
| SCHEMBL14277886 | 0.70 | PPARA (0.54) | PPARAPPARDPPARG | |
| SCHEMBL4575316 | 0.70 | PPARA (0.51) | PPARAPPARDPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7319104-B2 | hPPARs activators | SMITHKLINE BEECHAM CORPORATION (US) | 2008-01-15 | — | — | US | disclosed |
| US-20050137212-A1 | Hppars activators | SMITHKLINE BEECHAM CORPORATION | 2005-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050137212-A1 | Hppars activators | PPARG, PPARA, PPARD | PPARA 2/4885PPARD 3/4885PPARG 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.