⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4481979 | 0.79 | — | — | |
| SCHEMBL469710 | 0.76 | — | — | |
| SCHEMBL2489309 | 0.71 | — | — | |
| SCHEMBL5451526 | 0.69 | — | — | |
| SCHEMBL19873 | 0.67 | — | — | |
| SCHEMBL7659872 | 0.67 | — | — | |
| Ammonia Solution, Strong SCHEMBL30143496 | 0.65 | — | — | |
| SCHEMBL31432500 | 0.65 | — | — | |
| Hydrochloric Acid SCHEMBL30045549 | 0.65 | — | — | |
| Methane SCHEMBL15227989 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7442689-B2 | Cardioprotective phosphonates and malonates | MEDICURE INTERNATIONAL INC. (BB) | 2008-10-28 | — | — | US | disclosed |
| US-7105673-B2 | Cardioprotective phosphonates and malonates | MEDICURE INTERNATIONAL INC. (BB) | 2006-09-12 | — | — | US | disclosed |
| EP-1531157-A1 | Cardioprotective phosphonates | Medicure International Inc. (BB) | 2005-05-18 | — | — | EP | disclosed |
| US-6867215-B2 | Cardioprotective phosphonates and malonates | MEDICURE INTERNATIONAL INC. (BB) | 2005-03-15 | — | — | US | disclosed |
| US-20040171588-A1 | Cardioprotective phosphonates and malonates | MEDICURE INTERNATIONAL INC. (CA) | 2004-09-02 | — | — | US | disclosed |
| US-6780997-B2 | SUCH AS DIBENZYL(A,3-O-ISOPROPYLIDIENE-3-HYDROXY-4-HYDROXYMETHYL-2-METHYL-5-PYRIDYL) HYDROXYMETHYLPHOSPHONATE WHICH FUNCTIONS LIKE PYRIDOXAL-5'-PHOSPHATE IN VIVO; DRUG SCREENING; ANTIDIABETIC AGENTS | MEDICURE INTERNATIONAL INC. (BB) | 2004-08-24 | — | — | US | disclosed |
| US-6667315-B2 | Pyridoxine phosphonate analogues such as, for example, ((2-methyl-3-hydroxy-4-hydroxymethyl-5-pyridyl)alkylphosphonates, and (2-methyl-3-hydroxy-4-hydroxymethyl-5-pyridyl)azaalkylphosphonates) | MEDICURE INTERNATIONAL INC. (BA) | 2003-12-23 | — | — | US | disclosed |
| US-20030181422-A1 | Cardioprotective phosphonates and malonates | MEDICURE INTERNATIONAL INC. (BB) | 2003-09-25 | — | — | US | disclosed |
| US-6605612-B2 | Derivatives of 5-pyridylalkylphosphonates and 5-pyridylalkylmalonates useful drugs for treatment of cardiovascular related diseases and diabetes mellitus related diseases | MEDICURE INTERNATIONAL INC. (BB) | 2003-08-12 | — | — | US | disclosed |
| US-20030120074-A1 | Cardioprotective phosphonates and malonates | MEDICURE INTERNATIONAL INC. (BB) | 2003-06-26 | — | — | US | disclosed |
| US-20030114678-A1 | Cardioprotective phosphonates and malonates | MEDICURE INTERNATIONAL INC. (BB) | 2003-06-19 | — | — | US | disclosed |
| US-20030114677-A1 | Cardioprotective phosphonates and malonates | MEDICURE INTERNATIONAL INC. (BB) | 2003-06-19 | — | — | US | disclosed |
| EP-1268498-A1 | CARDIOPROTECTIVE PHOSPHONATES AND MALONATES | Medicure International Inc. (BB) | 2003-01-02 | — | — | EP | disclosed |
| US-20020010158-A1 | Cardioprotective phosphonates and malonates | MEDICURE INTERNATIONAL INC. (CA) | 2002-01-24 | — | — | US | disclosed |
| WO-2001064692-A1 | CARDIOPROTECTIVE PHOSPHONATES AND MALONATES | MEDICURE INTERNATIONAL INC. (BB) | 2001-09-07 | — | — | WO | disclosed |
| EP-0586575-A1 | DEGRADABLE CELLULOSE POLYMERS | BATTELLE MEMORIAL INSTITUTE (US) | 1994-03-16 | — | — | EP | disclosed |
| WO-1992020738-A1 | DEGRADABLE CELLULOSE POLYMERS | BATTELLE MEMORIAL INSTITUTE (US) | 1992-11-26 | — | — | WO | disclosed |