Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4577024 | 0.83 | TSHR (0.39) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL5071879 | 0.80 | TSHR (0.38) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL20423629 | 0.78 | TSHR (0.38) | TSHRHPGDALDH1A1CYP3A4SMN1; SMN2 | |
| SCHEMBL10325239 | 0.77 | TSHR (0.38) | TSHRHPGDSMN1; SMN2 | |
| SCHEMBL2144022 | 0.77 | TSHR (0.40) | TSHRCAMK2AALDH1A1CYP3A4SMN1; SMN2 | |
| SCHEMBL11341500 | 0.74 | CAMK2A (0.41) | TSHRCAMK2AALDH1A1 | |
| SCHEMBL28775510 | 0.74 | TSHR (0.34) | TSHRHPGDALDH1A1 | |
| SCHEMBL20210990 | 0.73 | TSHR (0.38) | TSHRHPGD | |
| SCHEMBL486886 | 0.73 | TSHR (0.38) | TSHRHPGD | |
| SCHEMBL28909748 | 0.72 | TSHR (0.45) | TSHRHPGDCAMK2AALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1807699-B1 | STRUCTURED COPOLYMER SUPPORTS FOR USE IN SPECTROMETRY OR SPECTROSCOPY | MAX PLANCK GESELLSCHAFT (DE) | 2008-12-31 | — | — | EP | disclosed |
| US-20080073511-A1 | Structured Copolymer Supports for Use in Mass Spectrometry | MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (US) | 2008-03-27 | — | — | US | disclosed |
| EP-1807699-A1 | STRUCTURED COPOLYMER SUPPORTS FOR USE IN MASS SPECTROMETRY | MPG Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2007-07-18 | — | — | EP | disclosed |
| WO-2006048306-A1 | STRUCTURED COPOLYMER SUPPORTS FOR USE IN MASS SPECTROMETRY | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2006-05-11 | — | — | WO | disclosed |