Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 8/20 | 0.55 |
| ▸ | HTT | P42858 | 7/20 | 0.55 |
| ▸ | MEN1 | O00255 | 6/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.55 |
| ▸ | LMNA | P02545 | 6/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | TP53 | P04637 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.55 |
| ▸ | USP2 | O75604 | 3/20 | 0.55 |
| ▸ | MMP14 | P50281 | 3/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.55 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL687239 | 0.88 | HSP90AA1 (0.58) | KDM4EHSP90AA1HTTMEN1KMT2A | |
| SCHEMBL3241364 | 0.88 | KDM4E (0.61) | KDM4EHSP90AA1HTTMEN1KMT2A | |
| SCHEMBL5473648 | 0.83 | HSP90AA1 (0.62) | KDM4EHSP90AA1HTTMEN1KMT2A | |
| SCHEMBL13313358 | 0.81 | KDM4E (0.59) | KDM4EHSP90AA1HTTMEN1KMT2A | |
| SCHEMBL18583574 | 0.81 | HSP90AA1 (0.57) | KDM4EHSP90AA1HTTMEN1KMT2A | |
| SCHEMBL12747809 | 0.81 | KDM4E (0.59) | KDM4EHSP90AA1HTTMEN1KMT2A | |
| SCHEMBL13313357 | 0.81 | HSP90AA1 (0.59) | KDM4EHSP90AA1HTTMEN1KMT2A | |
| SCHEMBL13313356 | 0.81 | HSP90AA1 (0.63) | KDM4EHSP90AA1HTTMEN1KMT2A | |
| SCHEMBL13271287 | 0.81 | KDM4E (0.50) | KDM4EHSP90AA1HTTMEN1KMT2A | |
| SCHEMBL5470672 | 0.80 | HSP90AA1 (0.59) | KDM4EHSP90AA1HTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1946397-A2 | ENZYMES IMMOBILIZED IN HYDROPHOBICALLY MODIFIED POLYSACCHARIDES | ST. LOUIS UNIVERSITY (US) | 2008-07-23 | — | — | EP | disclosed |
| WO-2007056666-A9 | ENZYMES IMMOBILIZED IN HYDROPHOBICALLY MODIFIED POLYSACCHARIDES | UNIV ST LOUIS (US) | 2007-11-01 | — | — | WO | disclosed |
| WO-2007056666-A2 | ENZYMES IMMOBILIZED IN HYDROPHOBICALLY MODIFIED POLYSACCHARIDES | ST. LOUIS UNIVERSITY (US) | 2007-05-18 | — | — | WO | disclosed |
| WO-2002102861-A2 | PROCESS FOR THE (CO)POLYMERIZATION OF CONJUGATED DIENES | ENI S.P.A. (IT) | 2002-12-27 | — | — | WO | disclosed |