SCHEMBL4579178

SCHEMBL4579178

C=CC(OC(=O)c1ccccc1)C(C)C

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.50
TP53 P04637 1/20 0.50
PDCD1 Q15116 1/20 0.49
CD274 Q9NZQ7 1/20 0.49
NPC1 O15118 5/20 0.46
LMNA P02545 4/20 0.46
RAB9A P51151 4/20 0.46
SMN1; SMN2 Q16637 3/20 0.46
HTT P42858 2/20 0.46
ALDH1A1 P00352 1/20 0.46
POLB P06746 2/20 0.44
F2 P00734 1/20 0.44
CYP1A2 P05177 1/20 0.41
CYP2D6 P10635 1/20 0.41
SCN1A P35498 1/20 0.41
SCN2A Q99250 1/20 0.41
SCN3A Q9NY46 1/20 0.41
AKT1 P31749 1/20 0.41
MAPT P10636 3/20 0.41
CA12 O43570 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28967378 0.84 TSHR (0.56) TSHRTP53PDCD1CD274NPC1
SCHEMBL30137644 0.84 TSHR (0.56) TSHRTP53PDCD1CD274NPC1
SCHEMBL9330992 0.82 TSHR (0.53) TSHRTP53PDCD1CD274NPC1
SCHEMBL3791059 0.78 TSHR (0.57) TSHRTP53PDCD1CD274NPC1
SCHEMBL14362156 0.78 TSHR (0.57) TSHRTP53PDCD1CD274NPC1
SCHEMBL5341762 0.77 TSHR (0.55) TSHRTP53PDCD1CD274NPC1
SCHEMBL17679380 0.76 TSHR (0.44) TSHRTP53PDCD1CD274NPC1
SCHEMBL2978163 0.76 TSHR (0.50) TSHRTP53PDCD1CD274NPC1
SCHEMBL14770956 0.76 TSHR (0.59) TSHRTP53PDCD1CD274NPC1
SCHEMBL14770954 0.76 TSHR (0.59) TSHRTP53PDCD1CD274NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130053469-A1 INK-JET PRINTER INK DURST PHOTOTECHNIK DIGITAL TECHNOLOGY GMBH (AT) 2013-02-28 US disclosed
US-7417009-B2 Paraffin inhibitors NALCO COMPANY (US) 2008-08-26 US disclosed
WO-2007076370-A2 BLOCK COPOLYMER PARTICLES BOSTON SCIENTIFIC SCIMED, INC. (US) 2007-07-05 WO disclosed
US-20050215437-A1 Paraffin inhibitors ECOLAB USA INC. 2005-09-29 US disclosed