SCHEMBL4579799

SCHEMBL4579799

C=C(CC=Cc1ccccc1)C(=O)OCCCCCC.C=CC(=O)OCCCCCCCCCCCCCCCCCC

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.46
HPGD P15428 1/20 0.46
ALDH1A1 P00352 2/20 0.42
CYP3A4 P08684 2/20 0.42
KDM4E B2RXH2 1/20 0.42
APP P05067 4/20 0.41
LMNA P02545 1/20 0.41
THRB P10828 2/20 0.40
THRA P10827 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
PAM P19021 1/20 0.40
EGFR P00533 1/20 0.39
TP53 P04637 1/20 0.39
MAPK1 P28482 1/20 0.39
HCAR2 Q8TDS4 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acrylic Acid Methyl Ester SCHEMBL10940540 0.94 KDM4E (0.43) TSHRHPGDALDH1A1CYP3A4KDM4E
Acrylic Acid SCHEMBL4579173 0.93 KDM4E (0.43) TSHRALDH1A1CYP3A4KDM4EAPP
SCHEMBL9442161 0.93 TSHR (0.47) TSHRALDH1A1CYP3A4KDM4EAPP
SCHEMBL7242327 0.93 TSHR (0.47) TSHRALDH1A1CYP3A4KDM4EAPP
SCHEMBL970624 0.92 TSHR (0.41) TSHRHPGDALDH1A1CYP3A4KDM4E
SCHEMBL9770214 0.91 TSHR (0.47) TSHRHPGDALDH1A1CYP3A4KDM4E
Acrylic Acid Ethyl Ester SCHEMBL7900245 0.91 TSHR (0.46) TSHRHPGDKDM4ELMNATHRB
SCHEMBL10942807 0.91 KDM4E (0.39) TSHRHPGDALDH1A1CYP3A4KDM4E
SCHEMBL4445828 0.89 TSHR (0.45) TSHRHPGDALDH1A1CYP3A4KDM4E
SCHEMBL11521409 0.89 HCAR2 (0.55) TSHRALDH1A1KDM4EAPPLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7417009-B2 Paraffin inhibitors NALCO COMPANY (US) 2008-08-26 US disclosed
WO-2005098200-A2 PARAFFIN INHIBITORS NALCO ENERGY SERVICES, L.P. (US) 2005-10-20 WO disclosed
US-20050215437-A1 Paraffin inhibitors ECOLAB USA INC. 2005-09-29 US disclosed