Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4578315 | 0.95 | EGFR (0.71) | EGFRKDR | |
| SCHEMBL4577760 | 0.90 | EGFR (0.70) | EGFRKDR | |
| SCHEMBL4578761 | 0.89 | EGFR (0.67) | EGFRKDR | |
| SCHEMBL4578763 | 0.89 | EGFR (0.67) | EGFRKDR | |
| SCHEMBL4577692 | 0.89 | EGFR (0.60) | EGFRKDR | |
| SCHEMBL4577813 | 0.89 | EGFR (0.62) | EGFRKDR | |
| SCHEMBL4599470 | 0.89 | EGFR (0.72) | EGFRKDR | |
| SCHEMBL4577710 | 0.88 | EGFR (0.71) | EGFRKDR | |
| SCHEMBL4579003 | 0.88 | EGFR (0.58) | EGFRKDR | |
| SCHEMBL5103549 | 0.88 | KDR (0.72) | EGFRKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1951686-A1 | QUINAZOLINE DERIVATIVES AS A MULTIPLEX INHIBITOR AND METHOD FOR THE PREPARATION THEREOF | Hanmi Pharm. Co., Ltd. (KR) | 2008-08-06 | — | — | EP | disclosed |
| WO-2007055514-A1 | QUINAZOLINE DERIVATIVES AS A MULTIPLEX INHIBITOR AND METHOD FOR THE PREPARATION THEREOF | HANMI PHARM. CO., LTD. (KR) | 2007-05-18 | — | — | WO | disclosed |