Methylpyrrolidone

Methylpyrrolidone

SCHEMBL4580849

CN1CCCC1=O.O=S1(=O)CCCC1

nearest known ligand 0.71

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.71
BRD2 P25440 1/20 0.71
INMT O95050 2/20 0.37
PIK3CD O00329 1/20 0.34
KMT2A Q03164 4/20 0.33
MEN1 O00255 3/20 0.33
GAA P10253 3/20 0.33
MAPT P10636 3/20 0.33
LMNA P02545 3/20 0.33
PSMD14 O00487 2/20 0.33
ALDH1A1 P00352 2/20 0.33
RAB9A P51151 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA3 P07451 1/20 0.33
CA4 P22748 1/20 0.33
CA6 P23280 1/20 0.33
CA5A P35218 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methylpyrrolidone SCHEMBL487 0.84
Methylpyrrolidone SCHEMBL8055062 0.84 BRD4 (1.00) BRD4BRD2INMTPIK3CDKMT2A
Methylpyrrolidone SCHEMBL5423326 0.84
Methylpyrrolidone SCHEMBL1255511 0.84 BRD4 (1.00) BRD4BRD2INMTPIK3CDKMT2A
Methylpyrrolidone SCHEMBL25409888 0.82
Methylpyrrolidone SCHEMBL12079053 0.82 BRD4 (0.94) BRD4BRD2INMTPIK3CDKMT2A
Methylpyrrolidone SCHEMBL8050526 0.82
Methylpyrrolidone SCHEMBL21599247 0.82
Methylpyrrolidone SCHEMBL5555743 0.82
Methylpyrrolidone SCHEMBL15347549 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102786497-A Preparation method of piperazine compound and intermediate thereof UNIV CHANGZHOU 2012-11-21 CN claimed
US-20210189064-A1 POLYISOINDOLINONES, METHODS OF MANUFACTURE, AND COMPOSITIONS AND ARTICLES FORMED THEREFROM SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2021-06-24 US disclosed
CN-109890871-A Method for producing aromatic polysulfone 住友化学株式会社 2019-06-14 CN disclosed
CN-109328207-A Aromatic series polysulfones and aromatic series polysulfone compositions 住友化学株式会社 2019-02-12 CN disclosed
CN-109312068-A aromatic polysulfone and aromatic polysulfone composition 住友化学株式会社 2019-02-05 CN disclosed
US-20080312349-A1 METHOD OF MAKING AND USING MEMBRANE GENERAL ELECTRIC COMPANY (US) 2008-12-18 US disclosed
WO-2008103599-A2 COMPOSITION, ITS USE IN THE PREPARATION OF MEMBRANES, AND SYSTEMS COMPRISING THE MEMBRANES SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2008-08-28 WO disclosed
US-20080203012-A1 MEMBRANE, APPARATUS, AND ASSOCIATED METHOD GENERAL ELECTRIC COMPANY (US) 2008-08-28 US disclosed