SCHEMBL45818

SCHEMBL45818

C=CC[NH]

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1359944 1.00
SCHEMBL132036 0.67
SCHEMBL16671468 0.60
SCHEMBL8990204 0.60
SCHEMBL12470940 0.60
SCHEMBL1328 0.59
SCHEMBL23546 0.59
SCHEMBL8852489 0.59 TSHR (0.54)
SCHEMBL23732 0.59
SCHEMBL23116592 0.56

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 12565 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024130646-A1 CARBOXYMETHYLATED LYSINE-BASED POLYMER AND COMPOSITIONS COMPRISING THE SAME BASF SE (DE) 2024-06-27 WO claimed
CN-118237170-A Flotation method of spodumene mineral 中国恩菲工程技术有限公司 2024-06-25 CN claimed
US-20240199542-A1 SUBSTITUTED PYRROLIDIN-2-ONES, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES BAYER AKTIENGESELLSCHAFT (DE) 2024-06-20 US claimed
US-20240199554-A1 INHIBITORS OF RECEPTOR INTERACTING PROTEIN KINASE I FOR THE TREATMENT OF DISEASE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 2024-06-20 US claimed
CN-118005611-A Probes for imaging huntingtin CHDI基金会股份有限公司 2024-05-10 CN claimed
WO-2024094163-A1 POLYCYCLIC RING-FUSED DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF 上海翰森生物医药科技有限公司 2024-05-10 WO claimed
CN-117794898-A 3-pyrrolylsulfonamide compounds as GPR17 antagonists 瑞文德医疗公众有限公司 2024-03-29 CN claimed
CN-117425661-A Macrocyclic LRRK2 kinase inhibitors 法国施维雅药厂 2024-01-19 CN claimed
CN-117384240-A HIV-1 capsid protein degradation agent based on hydrophobic tag technology and preparation method and application thereof 山东大学 2024-01-12 CN claimed
EP-3158578-B1 ADHESION LAYER COMPOSITION, METHOD FOR FORMING FILM BY NANOIMPRINTING, METHODS FOR MANUFACTURING OPTICAL COMPONENT, CIRCUIT BOARD AND ELECTRONIC APPARATUS CANON KK (JP) 2024-01-10 EP claimed
US-4234572-A AMINOGLYCOSIDE ANTIBIOTICS BAYER AKTIENGESELLSCHAFT (DE) 1980-11-18 US claimed
EP-0018674-A1 Benzodioxincarboxylic acid derivatives, their preparation and their inclusion in lipogenesis inhibiting compositions SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1980-11-12 EP claimed
EP-0018151-A1 6-Substituted-arylpyrido(2,3-d)pyrimidin-7-amines, derivatives and salts thereof, pharmaceutical compositions containing any of the foregoing, and processes for producing any of the foregoing WARNER-LAMBERT COMPANY (US) 1980-10-29 EP claimed
US-4228102-A FROM UNSATURATED ESTERS AND AMINES ROHM GMBH (DE) 1980-10-14 US claimed
WO-1980000796-A1 IMPROVEMENTS RELATING TO EXTRACTANTS FORD & DAIN RES (GB) 1980-05-01 WO claimed
EP-0008226-A2 Phenyl-alkanoic acid derivatives, the preparation thereof and pharmaceutical compositions containing them FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1980-02-20 EP claimed
US-4054572-A Hexahydro pyridine [1,2d] dibenza [b,f] (1,4)-diazepines AKZONA INCORPORATED (US) 1977-10-18 US claimed
US-4016161-A Amino-substituted 1,2,3,4,10,146-hexahydro-pyridino[1,2-a]dibenzo[c,f]azepines AKZONA INCORPORATED (US) 1977-04-05 US claimed
US-4001168-A Transparent storage-stable polysiloxanes which cross-link under atmospheric conditions BAYER AKTIENGESELLSCHAFT (DT) 1977-01-04 US claimed
US-3966723-A 1,2,3,4,10,14B-Hexahydro-pyridino[1,2-a]-dibenzo[c,f]-azepine AKZONA INCORPORATED (US) 1976-06-29 US claimed