SCHEMBL4582355

SCHEMBL4582355

O=[N+]([O-])c1sccc1Br

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL872076 0.74 PDE7A (0.46)
SCHEMBL11559307 0.73
SCHEMBL11537897 0.73
SCHEMBL826846 0.73
SCHEMBL10683668 0.73
SCHEMBL9125891 0.73
SCHEMBL8159398 0.73
Nitrogen SCHEMBL28031276 0.71 PDE7A (0.44)
SCHEMBL3710683 0.70 GSK3B (0.33)
SCHEMBL1057085 0.70 ERN1 (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4001284-B1 NOVEL BORON COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME SFC CO LTD (KR) 2025-12-10 EP disclosed
US-12415950-B2 Boron compound and organic light emitting diode including same SFC CO., LTD. (KR) 2025-09-16 US disclosed
US-20250109140-A1 5-[5-(PIPERIDIN-4-YL)THIENO[3,2-C]PYRAZOL-2-YL]INDAZOLE DERIVATIVES AND RELATED COMPOUNDS AS MODULATORS FOR SPLICING NUCLEIC ACIDS AND FOR THE TREATMENT OF PROLIFERATIVE DISEASES REMIX THERAPUTICS INC (US) 2025-04-03 US disclosed
US-20240239811-A1 5-(5-(PIPERIDIN-4-YL)THIENO[3,2-C]PYRAZOL-2-YL]INDAZOLE DERIVATIVES AND RELATED COMPOUNDS AS MODULATORS FOR SPLICING NUCLEIC ACIDS AND FOR THE T REMIX THERAPEUTICS INC. 2024-07-18 US disclosed
US-20240239811-A1 5-(5-(PIPERIDIN-4-YL)THIENO[3,2-C]PYRAZOL-2-YL]INDAZOLE DERIVATIVES AND RELATED COMPOUNDS AS MODULATORS FOR SPLICING NUCLEIC ACIDS AND FOR THE T REMIX THERAPEUTICS INC. 2024-07-18 US disclosed
CN-114040916-B Boron compound and organic light-emitting element comprising same SFC株式会社 2024-06-28 CN disclosed
EP-3872077-B1 HETEROCYCLIC AMIDE FOR INHIBITING RIP1 KINASE AND USES THEREOF SHANGHAI INST MATERIA MEDICA CAS (CN) 2024-06-12 EP disclosed
CN-113874015-B Thienopyridine inhibitors of RIPK2 细胞基因公司 2024-05-24 CN disclosed
EP-3897630-B1 THIENOPYRIDINE INHIBITORS OF RIPK2 CELGENE CORP (US) 2024-01-10 EP disclosed
CN-116940578-A 5- [5- (piperidin-4-yl) thieno [3,2-C ] pyrazol-2-yl ] indazole derivatives and related compounds as modulators for splicing nucleic acids and for the treatment of proliferative diseases 雷密克斯医疗公司 2023-10-24 CN disclosed
EP-0880511-A4 INTEGRIN RECEPTOR ANTAGONISTS MERCK & CO INC (US) 1999-06-16 EP disclosed
EP-0866705-A4 FIBRINOGEN RECEPTOR ANTAGONISTS MERCK & CO INC (US) 1999-03-03 EP disclosed
US-5852045-A Fibrinogen receptor antagonists MERCK & CO., INC. (US) 1998-12-22 US disclosed
EP-0880511-A1 INTEGRIN RECEPTOR ANTAGONISTS Merck & Co., Inc. (US) 1998-12-02 EP disclosed
EP-0866705-A1 FIBRINOGEN RECEPTOR ANTAGONISTS Merck & Co., Inc. (US) 1998-09-30 EP disclosed
US-5783597-A ANTIINFLAMMATORY AGENTS ORTHO PHARMACEUTICAL CORPORATION (US) 1998-07-21 US disclosed
US-5747518-A EFFECTIVE AGAINST CHEMICAL RESISTANT FUNGI; NONPHYTOTOXIC TO CROPS MITSUI TOATSU CHEMICALS, INC. (JP) 1998-05-05 US disclosed
WO-1997026250-A1 INTEGRIN RECEPTOR ANTAGONISTS MERCK & CO., INC. (US) 1997-07-24 WO disclosed
WO-1997014417-A1 FIBRINOGEN RECEPTOR ANTAGONISTS MERCK & CO., INC. (US) 1997-04-24 WO disclosed
EP-0737682-A1 Substituted thiophene derivative and agricultural and horticultural fungicide containing the same as active ingredient MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1996-10-16 EP disclosed