⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL451140 | 0.83 | GAA (0.30) | — | |
| SCHEMBL16315846 | 0.72 | — | — | |
| SCHEMBL8741627 | 0.71 | — | — | |
| SCHEMBL8721527 | 0.71 | — | — | |
| SCHEMBL14100048 | 0.71 | — | — | |
| SCHEMBL8212088 | 0.69 | — | — | |
| SCHEMBL26452808 | 0.67 | PAOX (0.37) | — | |
| SCHEMBL5317099 | 0.65 | POLB (0.32) | — | |
| SCHEMBL5313149 | 0.65 | POLB (0.32) | — | |
| SCHEMBL8974868 | 0.64 | GABRR1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010004454-A1 | Metal complexes derivatized with folate for use in diagnostic and therapeutic applications | BRACCO SUISSE SA (CH) | 2001-06-21 | — | — | US | claimed |
| US-7399460-B2 | Metal complexes derivatized with folate for use in diagnostic and therapeutic applications | BRACCO INTERNATIONAL B.V. (NL) | 2008-07-15 | — | — | US | disclosed |
| US-20070077197-A1 | Metal Complexes Derivatized with Folate for use in Diagnostic and Therapeutic Applications | BRACCO INTERNATIONAL B.V. (NL) | 2007-04-05 | — | — | US | disclosed |
| US-7186397-B2 | Metal complexes derivatized with folate for use in diagnostic and therapeutic applications | BRACCO INTERNATIONAL B.V. (NL) | 2007-03-06 | — | — | US | disclosed |
| US-20010004454-A1 | Metal complexes derivatized with folate for use in diagnostic and therapeutic applications | BRACCO SUISSE SA (CH) | 2001-06-21 | — | — | US | disclosed |
| US-6221334-B1 | Metal complexes derivatized with folate for use in diagnostic and therapeutic applications | BRACCO RESEARCH USA, INC. | 2001-04-24 | — | — | US | disclosed |
| US-6093382-A | A FOLATE-RECEPTOR BINDING LIGAND COMPRSING ONE OR MORE FOLATE BINDING GROUPS, ATLEAST ONE OF WHICH IS CONJUGATED THROUGH ALPHA CARBOXYLATE VIA A LINKING GROUP TO MACROCYCLIC OR NON MACROCYCLIC METAL CHELATING LIGAND RADICAL | BRACCO RESEARCH USA INC. (US) | 2000-07-25 | — | — | US | disclosed |