Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 19/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 16/20 | 0.44 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4582976 | 1.00 | ADRB3 (0.45) | ADRB3ADRB1CYP51A1 | |
| SCHEMBL4584860 | 0.96 | ADRB3 (0.46) | ADRB3ADRB1CYP51A1 | |
| SCHEMBL4584856 | 0.96 | ADRB3 (0.46) | ADRB3ADRB1CYP51A1 | |
| SCHEMBL1620529 | 0.91 | ADRB3 (0.56) | ADRB3ADRB1 | |
| SCHEMBL1620527 | 0.91 | ADRB3 (0.56) | ADRB3ADRB1 | |
| SCHEMBL4583928 | 0.89 | ADRB3 (0.53) | ADRB3ADRB1 | |
| SCHEMBL4583920 | 0.89 | ADRB3 (0.53) | ADRB3ADRB1 | |
| SCHEMBL1622910 | 0.87 | ADRB3 (0.47) | ADRB3ADRB1 | |
| SCHEMBL1621007 | 0.85 | ADRB3 (0.46) | ADRB3ADRB1 | |
| SCHEMBL1621003 | 0.85 | ADRB3 (0.46) | ADRB3ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7417060-B2 | Aminoalcohol derivatives | ASTELLAS PHARMA INC. (JP) | 2008-08-26 | — | — | US | disclosed |
| EP-1697301-A2 | AMINOALCOHOL DERIVATIVES | Astellas Pharma Inc. (JP) | 2006-09-06 | — | — | EP | disclosed |
| WO-2005061433-A2 | AMINOALCOHOL DERIVATIVES | ASTELLAS PHARMA INC. (JP) | 2005-07-07 | — | — | WO | disclosed |