Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.52 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.43 |
| ▸ | FPR1 | P21462 | 3/20 | 0.43 |
| ▸ | FPR2 | P25090 | 3/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | PRKDC | P78527 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 4/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | LIPE | Q05469 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14638305 | 1.00 | NOTUM (0.52) | NOTUMTLR7KDM4EHTTPDK2 | |
| SCHEMBL12895116 | 0.90 | NOTUM (0.59) | NOTUMPDK2AKR1C3CYP3A4CA12 | |
| SCHEMBL19012564 | 0.85 | HRH3 (0.43) | TLR7KDM4EHTTPDK2PRKDC | |
| SCHEMBL19571014 | 0.83 | NOTUM (0.49) | NOTUMAKR1C3CYP3A4CA12CA2 | |
| SCHEMBL15383528 | 0.81 | KDM4E (0.57) | NOTUMKDM4EHTTPRKDCTP53 | |
| SCHEMBL31145170 | 0.81 | KDM4E (0.57) | NOTUMKDM4EHTTPRKDCTP53 | |
| SCHEMBL24501932 | 0.81 | NOTUM (0.52) | NOTUMFPR1FPR2AKR1C3CYP3A4 | |
| SCHEMBL14638309 | 0.81 | NOTUM (0.52) | NOTUMFPR1FPR2AKR1C3CYP3A4 | |
| SCHEMBL14650198 | 0.81 | NOTUM (0.52) | NOTUMFPR1FPR2AKR1C3CYP3A4 | |
| SCHEMBL21624735 | 0.81 | NOTUM (0.52) | NOTUMFPR1FPR2AKR1C3CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1903023-A1 | Method for manufacturing arylamines | Archimica GmbH (DE) | 2008-03-26 | — | — | EP | disclosed |
| US-20080039633-A1 | Process for preparing arylamines | ARCHIMICA GMBH (DE) | 2008-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080039633-A1 | Process for preparing arylamines | BRD4, AHR, BRD1 | NOTUM 4211/4885TLR7 2151/4885KDM4E 2246/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.