Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 19/20 | 0.45 |
| ▸ | F2 | P00734 | 4/20 | 0.45 |
| ▸ | F11 | P03951 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4585098 | 0.98 | F10 (0.46) | F10F2F11LMNAKMT2A | |
| SCHEMBL8476746 | 0.91 | F10 (0.43) | F10F2F11LMNAKMT2A | |
| SCHEMBL3305811 | 0.88 | F10 (0.44) | F10F2F11LMNAKMT2A | |
| SCHEMBL8502118 | 0.88 | F10 (0.44) | F10F2F11LMNAKMT2A | |
| SCHEMBL13394834 | 0.88 | F10 (0.46) | F10F2F11KDM4EMEN1 | |
| SCHEMBL4582915 | 0.87 | F10 (0.46) | F10F2F11LMNAKMT2A | |
| SCHEMBL3309135 | 0.85 | F10 (0.45) | F10F2F11LMNAKMT2A | |
| SCHEMBL8487514 | 0.85 | F10 (0.45) | F10F2F11LMNAKMT2A | |
| SCHEMBL8476783 | 0.85 | F10 (0.47) | F10F2F11LMNAKMT2A | |
| SCHEMBL3308348 | 0.84 | F10 (0.45) | F10F2F11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2132193-B1 | SUBSTITUTED PYRROLIDINE AMIDES, THE PRODUCTION THEREOF, AND THE USE THEREOF AS MEDICATIONS | BOEHRINGER INGELHEIM INT (DE) | 2012-10-24 | — | — | EP | disclosed |
| EP-1975165-A1 | Substituted pyrrolidinamides, their production and utilisation as medicine | Boehringer Ingelheim Pharma GmbH & Co. KG (DE) | 2008-10-01 | — | — | EP | disclosed |