Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 1/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.64 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | CYP4B1 | P13584 | 1/20 | 0.64 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.64 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.64 |
| ▸ | CYP2A7 | P20853 | 1/20 | 0.64 |
| ▸ | CYP3A7 | P24462 | 1/20 | 0.64 |
| ▸ | CYP2F1 | P24903 | 1/20 | 0.64 |
| ▸ | CYP2C18 | P33260 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.64 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.64 |
| ▸ | CYP4F8 | P98187 | 1/20 | 0.64 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29740761 | 1.00 | CYP1A1 (0.64) | CYP1A1CYP1A2CYP2E1CYP3A4CYP2C8 | |
| SCHEMBL13247865 | 0.98 | ABL1 (0.64) | CYP1A1CYP1A2CYP2E1CYP3A4CYP2C8 | |
| Hydrochloric Acid SCHEMBL28963139 | 0.96 | CYP1A2 (0.59) | CYP1A1CYP1A2CYP2E1CYP3A4CYP2C8 | |
| Methylamine SCHEMBL27666960 | 0.96 | MAOB (0.61) | CYP1A1CYP1A2CYP2E1CYP3A4CYP2C8 | |
| Methyl Alcohol SCHEMBL28369741 | 0.96 | HDAC4 (0.59) | CYP1A1CYP1A2CYP2E1CYP3A4CYP2C8 | |
| Methane SCHEMBL28582279 | 0.96 | CYP1A2 (0.59) | CYP1A1CYP1A2CYP2E1CYP3A4CYP2C8 | |
| SCHEMBL28102064 | 0.96 | CYP1A2 (0.72) | CYP1A1CYP1A2CYP2E1CYP3A4CYP2C8 | |
| Formaldehyde SCHEMBL21629200 | 0.94 | HDAC4 (0.58) | CYP1A1CYP1A2CYP2E1CYP3A4CYP2C8 | |
| Cyanide SCHEMBL27973193 | 0.94 | CYP1A2 (0.57) | CYP1A1CYP1A2CYP2E1CYP3A4CYP2C8 | |
| SCHEMBL1180343 | 0.93 | ABL1 (0.69) | CYP1A1CYP1A2CYP2E1CYP3A4CYP2C8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 374 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113651758-B | Synthetic method of benzo-hydrogenated imidazolone framework | 南通大学 | 2023-03-14 | — | — | CN | claimed |
| CN-112300599-B | Hydrophilic anthracene fluorescent dye and synthetic method thereof | 赛纳生物科技(北京)有限公司 | 2023-01-03 | — | — | CN | claimed |
| CN-112831206-B | Inorganic oxide dispersion with controllable water content and preparation method thereof | 凯斯科技股份有限公司 | 2022-12-30 | — | — | CN | claimed |
| EP-3674303-B1 | NOVEL TRYPTOPHAN HYDROXYLASE INHIBITOR AND PHARMACEUTICAL COMPOSITION INCLUDING SAME | GWANGJU INST SCIENCE & TECH (KR) | 2022-07-20 | — | — | EP | claimed |
| CN-112300599-A | Hydrophilic anthracene fluorescent dye and synthetic method thereof | 赛纳生物科技(北京)有限公司 | 2021-02-02 | — | — | CN | claimed |
| CN-107556486-B | Rare earth organic framework material for iron ion fluorescence detection and preparation method thereof | 中国计量大学 | 2020-08-18 | — | — | CN | claimed |
| CN-109796312-A | A kind of synthetic method of 3- xenol | 上海阿拉丁生化科技股份有限公司 | 2019-05-24 | — | — | CN | claimed |
| EP-2001485-B1 | DIAZEPAN OREXIN RECEPTOR ANTAGONISTS | MERCK SHARP & DOHME (US) | 2015-09-09 | — | — | EP | claimed |
| EP-2049110-B1 | BRIDGED DIAZEPAN OREXIN RECEPTOR ANTAGONISTS | MERCK SHARP & DOHME (US) | 2014-08-20 | — | — | EP | claimed |
| US-8618102-B2 | Bridged diazepan orexin receptor antagonists | MERCK SHARP & DOHME CORP. (US) | 2013-12-31 | — | — | US | claimed |
| EP-1667958-A2 | MELANIN CONCENTRATING HORMONE ANTAGONISTS | THE PROCTER & GAMBLE COMPANY (US) | 2006-06-14 | — | — | EP | claimed |
| WO-2005033063-A2 | MELANIN CONCENTRATING HORMONE ANTAGONISTS | THE PROCTER & GAMBLE COMPANY (US) | 2005-04-14 | — | — | WO | claimed |
| US-20050075324-A1 | Melanin concentrating hormone antagonists | THE PROCTER & GAMBLE COMPANY (US) | 2005-04-07 | — | — | US | claimed |
| EP-1034164-B1 | SUBSTITUTED BETA-ALANINE DERIVATIVES AS CELL ADHESION INHIBITORS | MERCK & CO INC (US) | 2004-05-19 | — | — | EP | claimed |
| US-6645939-B1 | Very late antigen-4 (VLA) integrin antagonists; antiallergens, antiasthmatics, and antiinflammatory agents; multiple sclerosis, autoimmune disease treatment | MERCK & CO., INC. | 2003-11-11 | — | — | US | claimed |
| EP-1034164-A4 | SUBSTITUTED BETA-ALANINE DERIVATIVES AS CELL ADHESION INHIBITORS | MERCK & CO INC (US) | 2001-07-11 | — | — | EP | claimed |
| EP-1034164-A1 | SUBSTITUTED BETA-ALANINE DERIVATIVES AS CELL ADHESION INHIBITORS | Merck & Co., Inc. (US) | 2000-09-13 | — | — | EP | claimed |
| WO-1999026922-A1 | SUBSTITUTED PYRROLE DERIVATIVES AS CELL ADHESION INHIBITORS | MERCK & CO., INC. (US) | 1999-06-03 | — | — | WO | claimed |
| WO-1999026921-A1 | SUBSTITUTED β-ALANINE DERIVATIVES AS CELL ADHESION INHIBITORS | MERCK & CO., INC. (US) | 1999-06-03 | — | — | WO | claimed |
| WO-1999025707-A1 | 2-ARYLBENZO[b]THIOPHENES USEFUL FOR THE TREATMENT OF ESTROGEN DEPRIVATION SYNDROME | ELI LILLY AND COMPANY (US) | 1999-05-27 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050075324-A1 | Melanin concentrating hormone antagonists | MCHR1, MCHR2, MC1R | CYP1A1 1346/4885CYP1A2 690/4885CYP2E1 2389/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.