Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 19/20 | 0.54 |
| ▸ | ADRB1 | P08588 | 11/20 | 0.52 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4584551 | 1.00 | ADRB3 (0.54) | ADRB3ADRB1ADRB2SCN9A | |
| SCHEMBL4584309 | 0.90 | ADRB3 (0.64) | ADRB3ADRB1ADRB2 | |
| SCHEMBL4584317 | 0.90 | ADRB3 (0.64) | ADRB3ADRB1ADRB2 | |
| SCHEMBL4585998 | 0.90 | ADRB3 (0.64) | ADRB3ADRB1ADRB2 | |
| SCHEMBL4586007 | 0.90 | ADRB3 (0.64) | ADRB3ADRB1ADRB2 | |
| SCHEMBL4583815 | 0.89 | ADRB3 (0.64) | ADRB3ADRB1ADRB2 | |
| SCHEMBL4583820 | 0.89 | ADRB3 (0.64) | ADRB3ADRB1ADRB2 | |
| SCHEMBL4584603 | 0.89 | ADRB3 (0.63) | ADRB3ADRB1 | |
| SCHEMBL4584609 | 0.89 | ADRB3 (0.63) | ADRB3ADRB1 | |
| SCHEMBL4584535 | 0.87 | ADRB3 (0.53) | ADRB3ADRB1ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7417060-B2 | Aminoalcohol derivatives | ASTELLAS PHARMA INC. (JP) | 2008-08-26 | — | — | US | disclosed |