Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNK | O75909 | 3/20 | 0.42 |
| ▸ | CDK12 | Q9NYV4 | 3/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | KDM5A | P29375 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4582991 | 0.86 | CCNK (0.42) | CCNKCDK12F10KDM5AHDAC3 | |
| SCHEMBL13395041 | 0.85 | CCNK (0.43) | CCNKCDK12F10NOS3GAA | |
| SCHEMBL4584327 | 0.85 | CCNK (0.46) | CCNKCDK12F10KDM5ANAMPT | |
| SCHEMBL4582426 | 0.85 | CCNK (0.46) | CCNKCDK12F10KDM5ANAMPT | |
| SCHEMBL4584897 | 0.85 | CCNK (0.46) | CCNKCDK12F10KDM5ANAMPT | |
| SCHEMBL4583904 | 0.85 | CCNK (0.42) | CCNKCDK12F10KDM5AHDAC3 | |
| SCHEMBL4435735 | 0.82 | CCNK (0.40) | CCNKCDK12F10KDM5AHDAC3 | |
| SCHEMBL4582199 | 0.82 | CCNK (0.46) | CCNKCDK12F10KDM5ANAMPT | |
| SCHEMBL4584467 | 0.81 | CCNK (0.40) | CCNKCDK12F10KDM5ANAMPT | |
| SCHEMBL4583666 | 0.81 | CCNK (0.43) | CCNKCDK12F10KDM5APDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2132193-B1 | SUBSTITUTED PYRROLIDINE AMIDES, THE PRODUCTION THEREOF, AND THE USE THEREOF AS MEDICATIONS | BOEHRINGER INGELHEIM INT (DE) | 2012-10-24 | — | — | EP | disclosed |
| EP-1975165-A1 | Substituted pyrrolidinamides, their production and utilisation as medicine | Boehringer Ingelheim Pharma GmbH & Co. KG (DE) | 2008-10-01 | — | — | EP | disclosed |