Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RORA | P35398 | 5/20 | 0.39 |
| ▸ | RORC | P51449 | 5/20 | 0.39 |
| ▸ | RORB | Q92753 | 5/20 | 0.39 |
| ▸ | PGR | P06401 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15057621 | 1.00 | TDP1 (0.45) | TDP1L3MBTL1KDM4EALDH1A1HPGD | |
| SCHEMBL13280761 | 1.00 | TDP1 (0.45) | TDP1L3MBTL1KDM4EALDH1A1HPGD | |
| SCHEMBL15057939 | 1.00 | TDP1 (0.45) | TDP1L3MBTL1KDM4EALDH1A1HPGD | |
| SCHEMBL15057631 | 0.94 | TDP1 (0.46) | TDP1L3MBTL1KDM4EALDH1A1HPGD | |
| SCHEMBL3855630 | 0.94 | TDP1 (0.46) | TDP1L3MBTL1KDM4EALDH1A1HPGD | |
| SCHEMBL19052071 | 0.91 | TDP1 (0.42) | TDP1L3MBTL1KDM4EALDH1A1HPGD | |
| SCHEMBL19052075 | 0.90 | TDP1 (0.41) | TDP1L3MBTL1KDM4EALDH1A1HPGD | |
| SCHEMBL19052076 | 0.85 | TDP1 (0.50) | TDP1L3MBTL1KDM4EALDH1A1HPGD | |
| SCHEMBL54244 | 0.85 | TDP1 (0.59) | TDP1L3MBTL1KDM4EALDH1A1HPGD | |
| SCHEMBL15057066 | 0.85 | TDP1 (0.59) | TDP1L3MBTL1KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080021220-A1 | Naphthalene-based semiconductor materials and methods of preparing and use thereof | POLYERA CORPORATION | 2008-01-24 | — | — | US | claimed |
| WO-2007146250-A2 | NAPHTHALENE-BASED SEMICONDUCTOR MATERIALS AND METHODS OF PREPARING AND USE THEREOF | NORTHWESTERN UNIVERSITY (US) | 2007-12-21 | — | — | WO | claimed |
| WO-2013096924-A1 | OLIGOMERS AND POLYMERS AND POLYMERS AND METHODS DERIVED FROM STANNYL DERIVATIVES OF NAPHTHALENE DIIMIDES | GEORGIA TECH RESEARCH CORPORATION (US) | 2013-06-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080021220-A1 | Naphthalene-based semiconductor materials and methods of preparing and use thereof | NES, NUCB2, NCL | TDP1 1917/4885L3MBTL1 3966/4885KDM4E 742/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.