⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21810512 | 0.90 | — | — | |
| SCHEMBL191208 | 0.78 | — | — | |
| SCHEMBL18091111 | 0.67 | — | — | |
| SCHEMBL3481754 | 0.67 | — | — | |
| SCHEMBL9078731 | 0.64 | — | — | |
| SCHEMBL4927872 | 0.61 | — | — | |
| SCHEMBL21723092 | 0.61 | — | — | |
| SCHEMBL8217974 | 0.61 | — | — | |
| SCHEMBL8840875 | 0.61 | — | — | |
| SCHEMBL31613457 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020119205-A1 | RADIOACTIVE FLUORINE-LABELED LAROTRECTINIB COMPOUND AND PREPARATION METHOD THEREFOR | 上海健康医学院 | 2020-06-18 | — | — | WO | claimed |
| EP-0686150-B1 | Process for the preparation of C-nucleosides and C-nucleoside analogues, new C-nucleosides and C-nucleoside analogues and their use | MAX DELBRUECK CENTRUM (DE) | 1998-05-20 | — | — | EP | claimed |
| EP-0422570-B1 | Ultraviolet light sensitive photoinitiator compositions, use thereof and radiation sensitive compositions | IBM (US) | 1995-12-27 | — | — | EP | claimed |
| US-5098816-A | Method for forming a pattern of a photoresist | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 1992-03-24 | — | — | US | claimed |
| US-5059512-A | ULTRAVIOLET LIGHT SENSITIVE PHOTOINITIATOR COMPOSITIONS, USE THEREOF AND RADIATION SENSITIVE COMPOSITIONS | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 1991-10-22 | — | — | US | claimed |
| CN-118878466-A | Trifluoro-azole and its preparation method | 特里纳普克公司 | 2024-11-01 | — | — | CN | disclosed |
| CN-115038692-B | Trifluoro-azole and its preparation method | 特里纳普克公司 | 2024-07-16 | — | — | CN | disclosed |
| CN-118119594-A | Camptothecin derivative intermediate, preparation method and application thereof | 上海弼领生物技术有限公司 | 2024-05-31 | — | — | CN | disclosed |
| CN-115038692-A | Trifluozole and preparation method thereof | 特里纳普克公司 | 2022-09-09 | — | — | CN | disclosed |
| CN-109705124-B | Radioactive fluorine labeled Larotrectinib compound and preparation method thereof | 上海健康医学院 | 2021-09-24 | — | — | CN | disclosed |
| EP-2573854-B1 | NON-AQUEOUS ELECTROLYTE SOLUTION CONTAINING SILYL ESTER GROUP-CONTAINING PHOSPHONIC ACID DERIVATIVE, AND LITHIUM SECONDARY BATTERY | MITSUI CHEMICALS INC (JP) | 2017-01-04 | — | — | EP | disclosed |
| CN-103402988-A | Compositions for inhibiting insect host perception | UNIV VANDERBILT | 2013-11-20 | — | — | CN | disclosed |
| EP-0422570-A2 | Ultraviolet light sensitive photoinitiator compositions, use thereof and radiation sensitive compositions | International Business Machines Corporation (US) | 1991-04-17 | — | — | EP | disclosed |
| US-4990612-A | 16α-methylation process | THE UPJOHN COMPANY (US) | 1991-02-05 | — | — | US | disclosed |
| EP-0165037-B1 | 16 ALPHA-METHYL STEROIDS AND THEIR PREPARATION | THE UPJOHN COMPANY (US) | 1990-09-19 | — | — | EP | disclosed |
| US-4929395-A | 16α-methylation process | THE UPJOHN COMPANY (US) | 1990-05-29 | — | — | US | disclosed |
| US-4891426-A | EPOXIDATION WITH PERACID | THE UPJOHN COMPANY (US) | 1990-01-02 | — | — | US | disclosed |
| US-4704455-A | 16α-methylatedΔ17(20)-corticoids | THE UPJOHN COMPANY (US) | 1987-11-03 | — | — | US | disclosed |
| EP-0165037-A2 | 16 alpha-methyl steroids and their preparation | THE UPJOHN COMPANY (US) | 1985-12-18 | — | — | EP | disclosed |
| US-4036831-A | Trimethyl siloxane steroid intermediates | STEROID DEVELOPMENT COMPANY ESTABLISHMENT (CH) | 1977-07-19 | — | — | US | disclosed |