SCHEMBL4585892

SCHEMBL4585892

CCCCCCCCCCNC(=O)Cc1ccccc1

nearest known ligand 0.80

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 5/20 0.73
HPGD P15428 3/20 0.69
GAA P10253 1/20 0.68
ATM Q13315 1/20 0.66
MEN1 O00255 1/20 0.65
KMT2A Q03164 1/20 0.65
NAAA Q02083 1/20 0.61
NAMPT P43490 1/20 0.59
ALDH1A1 P00352 1/20 0.59
CNR2 P34972 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28082833 1.00 TRPV1 (0.73) TRPV1HPGDGAAATMMEN1
SCHEMBL28083065 1.00 TRPV1 (0.73) TRPV1HPGDGAAATMMEN1
SCHEMBL28083130 1.00 TRPV1 (0.73) TRPV1HPGDGAAATMMEN1
SCHEMBL28082736 1.00 TRPV1 (0.73) TRPV1HPGDGAAATMMEN1
SCHEMBL8210207 1.00 TRPV1 (0.73) TRPV1HPGDGAAATMMEN1
SCHEMBL4585546 1.00 TRPV1 (0.73) TRPV1HPGDGAAATMMEN1
SCHEMBL8197547 1.00 TRPV1 (0.73) TRPV1HPGDGAAATMMEN1
SCHEMBL9321740 1.00 TRPV1 (0.73) TRPV1HPGDGAAATMMEN1
SCHEMBL3994188 1.00 TRPV1 (0.73) TRPV1HPGDGAAATMMEN1
SCHEMBL28082834 1.00 TRPV1 (0.73) TRPV1HPGDGAAATMMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105814092-B Composition for hydrophilic cured product 三井化学株式会社 2018-09-21 CN disclosed
CN-107250226-A Acrylic resin modified solidfied material and its layered product and their manufacture method 三井化学株式会社 2017-10-13 CN disclosed
CN-105814092-A Composition for hydrophilic cured product 三井化学株式会社 2016-07-27 CN disclosed
WO-2008113992-A2 GEL COMPOSITIONS COMPRISING UREA DERIVATIVES PLIVA HRVATSKA D.O.O. (HR) 2008-09-25 WO disclosed
US-6117840-A INHIBITS BINDING BETWEEN VLA-4 RECEPTOR EXPRESSED ON INFLAMMATORY LEUKOCYTES AND FIBRONECTIN CS-1 PEPTIDE EXPRESSED ON ENDOTHELIAL CELLS THAT ARE INVOLVED IN IMMUNOINFLAMMATORY DISEASE STATES CYTEL CORPORATION (US) 2000-09-12 US disclosed
US-6103870-A INHIBITS BINDING BETWEEN VLA-4 RECEPTOR EXPRESSED ON INFLAMMATORY LEUKOCYTES AND FIBRONECTIN CS-1 PEPTIDE EXPRESSED ON ENDOTHELIAL CELLS; ANTIINFLAMMATORY AGENTS; ANTIARTHRITIC AGENTS; TREATMENT OF ASTHMA CYTEL CORPORATION (US) 2000-08-15 US disclosed
WO-2000002903-A1 CS-1 PEPTIDOMIMETICS, COMPOSITIONS AND METHODS OF USING THE SAME CYTEL CORPORATION (US) 2000-01-20 WO disclosed
US-5936065-A PRODRUG AS ANTIINFLAMMATORY AGENT FOR AUTOIMMUNE DISEASES; FOR SUPPRESSING BINDING OF INFLAMMATORY CELLS TO ENDOTHELIAL CELLS THAT EXPRESS THE CS-1 PORTION OF FIBRONECTIN ON THEIR SURFACES CYTEL CORPORATION (US) 1999-08-10 US disclosed
US-5821231-A TREATMENT OF IMMUNOINFLAMMATORY CONDITIONS CYTEL CORPORATION (US) 1998-10-13 US disclosed
US-5770573-A CS-1 peptidomimetics, compositions and methods of using the same CYTEL CORPORATION (US) 1998-06-23 US disclosed
US-5688913-A OLIGOPEPTIDES AS ANTIINFLAMMATORY AGENTS CYTEL CORPORATION (US) 1997-11-18 US disclosed