Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 20/20 | 0.64 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.62 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4586957 | 0.87 | HDAC1 (0.69) | HDAC1HDAC2HDAC3 | |
| SCHEMBL4506680 | 0.83 | HDAC1 (0.66) | HDAC1HDAC2HDAC3 | |
| SCHEMBL4589159 | 0.81 | HDAC1 (0.69) | HDAC1HDAC2HDAC3 | |
| SCHEMBL4578426 | 0.81 | HDAC1 (0.76) | HDAC1HDAC2HDAC3 | |
| SCHEMBL4318134 | 0.81 | HDAC1 (0.65) | HDAC1HDAC2HDAC3 | |
| SCHEMBL4579079 | 0.80 | HDAC1 (0.75) | HDAC1HDAC2HDAC3 | |
| SCHEMBL4525067 | 0.80 | HDAC1 (0.64) | HDAC1HDAC2HDAC3 | |
| SCHEMBL2692243 | 0.80 | HDAC1 (0.70) | HDAC1HDAC2HDAC3 | |
| SCHEMBL4451154 | 0.80 | HDAC1 (0.70) | HDAC1HDAC2HDAC3 | |
| SCHEMBL2206760 | 0.79 | HDAC1 (0.74) | HDAC1HDAC2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1973405-A2 | HYDROXYALKYLARYLAMIDE DERIVATIVES | Merck & Co., Inc. (US) | 2008-10-01 | — | — | EP | claimed |
| WO-2007087130-A2 | HYDROXYALKYLARYLAMIDE DERIVATIVES | MERCK & CO., INC. (US) | 2007-08-02 | — | — | WO | claimed |