Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 1/20 | 0.38 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.31 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.31 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6364327 | 1.00 | GRM1 (0.38) | GRM1SLC7A5PTGS1SLC7A11GRIK1 | |
| SCHEMBL4587196 | 1.00 | GRM1 (0.38) | GRM1SLC7A5PTGS1SLC7A11GRIK1 | |
| SCHEMBL19143631 | 0.84 | GSR (0.35) | GRM1GRIK1GRIK2 | |
| SCHEMBL26668147 | 0.78 | GRM1 (0.39) | GRM1SLC7A5PTGS1SLC7A11GRIK1 | |
| SCHEMBL29371043 | 0.78 | GRM1 (0.39) | GRM1SLC7A5PTGS1SLC7A11GRIK1 | |
| SCHEMBL10606654 | 0.77 | GNPAT (0.32) | — | |
| SCHEMBL4543133 | 0.77 | — | — | |
| SCHEMBL1829757 | 0.77 | GRM1 (0.38) | GRM1SLC7A5PTGS1SLC7A11 | |
| SCHEMBL1829760 | 0.77 | GRM1 (0.38) | GRM1SLC7A5PTGS1SLC7A11 | |
| SCHEMBL6070073 | 0.77 | GRM1 (0.38) | GRM1SLC7A5PTGS1SLC7A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1737884-A4 | ALPHA HELICAL MIMICS, THEIR USES AND METHODS FOR THEIR PRODUCTION | UNIV QUEENSLAND (AU) | 2008-10-29 | — | — | EP | disclosed |
| EP-1963362-A1 | METASTIN DERIVATIVES AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2008-09-03 | — | — | EP | disclosed |
| WO-2007072997-A1 | METASTIN DERIVATIVES AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-06-28 | — | — | WO | disclosed |
| EP-1737884-A1 | ALPHA HELICAL MIMICS, THEIR USES AND METHODS FOR THEIR PRODUCTION | The University of Queensland (AU) | 2007-01-03 | — | — | EP | disclosed |
| WO-2005090388-A1 | ALPHA HELICAL MIMICS, THEIR USES AND METHODS FOR THEIR PRODUCTION | THE UNIVERSITY OF QUEENSLAND (AU) | 2005-09-29 | — | — | WO | disclosed |
| WO-2004058804-A1 | PEPTIDES AND THERAPEUTIC USES THEREOF | WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH (AU) | 2004-07-15 | — | — | WO | disclosed |
| WO-2002088184-A9 | A MOLECULAR MARKER | MURDOCH CHILDRENS RES INST (AU) | 2004-02-19 | — | — | WO | disclosed |