Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 5/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.38 |
| ▸ | DHFR | P00374 | 8/20 | 0.33 |
| ▸ | DCPS | Q96C86 | 8/20 | 0.33 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.33 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.33 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.33 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.33 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.33 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.33 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.33 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3977482 | 0.86 | TLR7 (0.37) | TLR7TLR8DHFRADORA3ADORA2A | |
| SCHEMBL3862404 | 0.86 | TLR8 (0.37) | TLR7TLR8CSNK1A1CSNK1DPRKCD | |
| Hydrochloric Acid SCHEMBL9134401 | 0.85 | TLR7 (0.36) | TLR7TLR8DHFRADORA2A | |
| SCHEMBL5507090 | 0.81 | ELANE (0.33) | TLR7TLR8CSNK1A1CSNK1DPRKCD | |
| SCHEMBL8322469 | 0.80 | HTT (0.36) | TLR7TLR8 | |
| SCHEMBL9388928 | 0.76 | TLR8 (0.35) | TLR7TLR8CSNK1A1CSNK1DPRKCD | |
| SCHEMBL5271662 | 0.76 | TLR8 (0.43) | TLR8DHFRCSNK1A1CSNK1DPRKCD | |
| SCHEMBL1692289 | 0.75 | TLR7 (0.39) | TLR7TLR8DHFRCSNK1A1CSNK1D | |
| SCHEMBL18588106 | 0.75 | TLR8 (0.42) | TLR7TLR8DHFRCSNK1A1CSNK1D | |
| SCHEMBL4654594 | 0.73 | TLR7 (0.39) | TLR7TLR8DCPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1685129-A4 | OXIME SUBSTITUTED IMIDAZO RING COMPOUNDS | 3M INNOVATIVE PROPERTIES CO (US) | 2008-10-22 | — | — | EP | disclosed |
| EP-1685129-A2 | OXIME SUBSTITUTED IMIDAZO RING COMPOUNDS | 3M Innovative Properties Company (US) | 2006-08-02 | — | — | EP | disclosed |
| WO-2005048933-A2 | OXIME SUBSTITUTED IMIDAZO RING COMPOUNDS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2005-06-02 | — | — | WO | disclosed |