Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 20/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4585159 | 0.89 | CALCRL (0.70) | CALCRL | |
| SCHEMBL6135930 | 0.84 | CALCRL (0.55) | CALCRL | |
| SCHEMBL3598767 | 0.83 | CALCRL (1.00) | CALCRL | |
| SCHEMBL13052659 | 0.83 | CALCRL (1.00) | CALCRL | |
| SCHEMBL4594334 | 0.83 | CALCRL (0.64) | CALCRL | |
| SCHEMBL4585089 | 0.82 | CALCRL (0.57) | CALCRL | |
| SCHEMBL4585560 | 0.82 | CALCRL (0.68) | CALCRL | |
| SCHEMBL4594168 | 0.81 | CALCRL (0.69) | CALCRL | |
| SCHEMBL6135609 | 0.81 | CALCRL (0.71) | CALCRL | |
| SCHEMBL4585177 | 0.81 | CALCRL (0.59) | CALCRL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1689493-A4 | CALCITONIN GENE RELATED PEPTIDE RECEPTOR ANTAGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2008-04-23 | — | — | EP | disclosed |
| EP-1689493-A1 | CALCITONIN GENE RELATED PEPTIDE RECEPTOR ANTAGONISTS | Bristol-Myers Squibb Pharma Company (US) | 2006-08-16 | — | — | EP | disclosed |
| WO-2005065779-A1 | CALCITONIN GENE RELATED PEPTIDE RECEPTOR ANTAGONISTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-07-21 | — | — | WO | disclosed |