SCHEMBL458748

SCHEMBL458748

O=C(Nc1cc(Cl)ccc1-c1ccccc1)c1cccnc1Cl

nearest known ligand 0.73

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 1/20 0.73
▸ IRAK4 Q9NWZ3 5/20 0.63
▸ GAA P10253 2/20 0.57
▸ MEN1 O00255 1/20 0.53
▸ KMT2A Q03164 1/20 0.53
▸ RXFP1 Q9HBX9 2/20 0.53
▸ KDM4E B2RXH2 1/20 0.53
▸ L3MBTL1 Q9Y468 1/20 0.53
▸ ALDH1A1 P00352 2/20 0.52
▸ HPGD P15428 2/20 0.52
▸ MAPT P10636 2/20 0.49
▸ FABP4 P15090 1/20 0.49
▸ TP53 P04637 1/20 0.49
▸ GFER P55789 1/20 0.49
▸ SMN1; SMN2 Q16637 3/20 0.48
▸ HTT P42858 1/20 0.48
▸ KDR P35968 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30385229 1.00 TDP1 (0.73) TDP1IRAK4GAAMEN1KMT2A
SCHEMBL28385052 0.89 IRAK4 (0.62) TDP1IRAK4MEN1KMT2AALDH1A1
SCHEMBL8074225 0.87 TDP1 (0.85) TDP1IRAK4GAAMEN1KMT2A
Boscalid SCHEMBL22444559 0.86 TDP1 (0.93) TDP1IRAK4GAARXFP1KDM4E
SCHEMBL15843974 0.85 TDP1 (0.60) TDP1IRAK4GAAMEN1KMT2A
Boscalid SCHEMBL29488452 0.85 TDP1 (1.00) TDP1IRAK4GAAMEN1KMT2A
Boscalid SCHEMBL29368300 0.85 TDP1 (1.00) TDP1IRAK4GAAMEN1KMT2A
Boscalid SCHEMBL18517 0.85 TDP1 (1.00) TDP1IRAK4GAAMEN1KMT2A
SCHEMBL28002383 0.84 TDP1 (0.58) TDP1IRAK4GAAKMT2ARXFP1
Boscalid SCHEMBL3619333 0.84 TDP1 (0.97) TDP1IRAK4GAAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1659864-B1 METHOD OF PLANT GROWTH PROMOTION USING AMIDE COMPOUNDS BASF SE (DE) 2013-09-18 — — EP claimed
JP-2007503403-A — — 2007-02-22 — — JP claimed
US-20060211574-A1 Method of plant growth promotion using amide compounds BASF AKTIENGESELLSCHAFT (DE) 2006-09-21 — — US claimed
EP-1659864-A2 METHOD OF PLANT GROWTH PROMOTION USING AMIDE COMPOUNDS BASF AKTIENGESELLSCHAFT (DE) 2006-05-31 — — EP claimed
WO-2005018324-A2 METHOD OF PLANT GROWTH PROMOTION USING AMIDE COMPOUNDS BASF AKTIENGESELLSCHAFT (DE) 2005-03-03 — — WO claimed
CN-116784327-A Bactericide composition containing SDHI bactericides 华南理工大学 2023-09-22 — — CN disclosed
CN-116261952-A Suspending agent containing boscalid and cyprodinil and preparation method thereof 山东润博生物科技有限公司 2023-06-16 — — CN disclosed
CN-114634444-A Preparation method of amide compound 泰州百力化学股份有限公司 2022-06-17 — — CN disclosed
EP-3789017-A1 COMPOSITIONS AND METHODS USING CAPSIDS RESISTANT TO HYDROLASES APSE LLC (US) 2021-03-10 — — EP disclosed
CN-111235194-A Preparation method of boscalid 安徽赛乐普制药有限公司 2020-06-05 — — CN disclosed
WO-2017050428-A9 NOVEL PLANT PROTECTING COMPOSITIONS AND USES THEREOF FLECHSIG PATENT COMPANY LLC (CH) 2018-07-19 — — WO disclosed
EP-1659864-B1 METHOD OF PLANT GROWTH PROMOTION USING AMIDE COMPOUNDS BASF SE (DE) 2013-09-18 — — EP disclosed
WO-2005018324-A2 METHOD OF PLANT GROWTH PROMOTION USING AMIDE COMPOUNDS BASF AKTIENGESELLSCHAFT (DE) 2005-03-03 — — WO disclosed
EP-1432685-A1 CRYSTALLINE HYDRATES OF NICOTINIC ACID ANILIDE AND BENZOYL ANILIDE DERIVATIVES BASF AKTIENGESELLSCHAFT (DE) 2004-06-30 — — EP disclosed
EP-1412356-A1 SUBSTITUTED 6-(2-METHOXYPHENYL)TRIAZOLOPYRIMIDINES AS FUNGICIDES BASF AKTIENGESELLSCHAFT (DE) 2004-04-28 — — EP disclosed
EP-1412358-A1 6-(2,6-DIFLUOROPHENYL)-TRIAZOLOPYRIMIDINES AS FUNGICIDES BASF AKTIENGESELLSCHAFT (DE) 2004-04-28 — — EP disclosed
WO-2003008417-A9 SUBSTITUTED 6-(2-TOLYL)-TRIAZOLOPYRIMIDINES AS FUNGICIDES BASF AG (DE) 2003-10-30 — — WO disclosed
WO-2003029219-A1 CRYSTALLINE HYDRATES OF NICOTINIC ACID ANILIDE AND BENZOYL ANILIDE DERIVATIVES BASF AKTIENGESELLSCHAFT (DE) 2003-04-10 — — WO disclosed
WO-2003008415-A1 6-(2,6-DIFLUOROPHENYL)-TRIAZOLOPYRIMIDINES AS FUNGICIDES BASF AKTIENGESELLSCHAFT (DE) 2003-01-30 — — WO disclosed
WO-2003008416-A1 SUBSTITUTED 6-(2-METHOXYPHENYL) TRIAZOLOPYRIMIDES AS FUNGICIDES BASF AKTIENGESELLSCHAFT (DE) 2003-01-30 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060211574-A1 Method of plant growth promotion using amide compounds CBR3, CNR2, CBR1 TDP1 4848/4885IRAK4 4797/4885GAA 3761/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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