Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Chloroacetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 6/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Chloroacetic Acid SCHEMBL6348583 | 0.96 | — | — | |
| Chloroacetic Acid SCHEMBL6342133 | 0.96 | — | — | |
| Chloroacetic Acid SCHEMBL21752872 | 0.96 | CA4 (0.50) | CA4TSHRCASP1FFAR3HDAC3 | |
| Chloroacetic Acid SCHEMBL6908147 | 0.92 | CA4 (0.47) | CA4TSHRCASP1FFAR3HDAC3 | |
| Chloroacetic Acid SCHEMBL21752985 | 0.92 | CA4 (0.47) | CA4TSHRCASP1FFAR3HDAC3 | |
| Chloroacetic Acid SCHEMBL8587680 | 0.92 | CA4 (0.47) | CA4TSHRCASP1FFAR3HDAC3 | |
| Chloroacetic Acid SCHEMBL379061 | 0.92 | CA4 (0.47) | CA4TSHRCASP1FFAR3HDAC3 | |
| Chloroacetic Acid SCHEMBL21752867 | 0.92 | — | — | |
| Chloroacetic Acid SCHEMBL8608083 | 0.92 | CA4 (0.47) | CA4TSHRCASP1FFAR3HDAC3 | |
| Chloroacetic Acid SCHEMBL6915345 | 0.92 | CA4 (0.47) | CA4TSHRCASP1FFAR3HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11434379-B2 | Composition, its preparation process, and the use of the composition as a waterproofing coat | BASF SE (DE) | 2022-09-06 | — | — | US | claimed |
| US-20220081509-A1 | A COMPOSITION COMPRISING METHYLENE MALONATE MONOMER AND POLYMER, THE PREPARATION THEREOF AND USE OF THE SAME IN UNDERGROUND CONSTRUCTIONS | BASF SE (DE) | 2022-03-17 | — | — | US | claimed |
| CN-114058173-A | Process and composition for producing flexible polyurethane foams | 赢创运营有限公司 | 2022-02-18 | — | — | CN | claimed |
| EP-3954722-A1 | PROCESS AND COMPOSITION FOR THE PRODUCTION OF FLEXIBLE POLYURETHANE FOAM | Evonik Operations GmbH (DE) | 2022-02-16 | — | — | EP | claimed |
| US-20220033603-A1 | PROCESS AND COMPOSITION FOR THE PRODUCTION OF FLEXIBLE POLYURETHANE FOAM | EVONIK OPERATIONS GMBH (DE) | 2022-02-03 | — | — | US | claimed |
| CN-113454169-A | Compositions comprising methylene malonate monomers and polymers, methods of making the same, and uses thereof in subterranean construction | 巴斯夫欧洲公司 | 2021-09-28 | — | — | CN | claimed |
| US-20210222118-A1 | CHARCOAL-FREE CULTURE MEDIA FOR LEGIONELLA | Secretary of State for Health and Social Care (GB) | 2021-07-22 | — | — | US | claimed |
| EP-3841214-A1 | CHARCOAL-FREE CULTURE MEDIA FOR LEGIONELLA | Secretary of State for Health and Social Care (GB) | 2021-06-30 | — | — | EP | claimed |
| CN-112888790-A | Legionella carbon-free culture medium | 英国卫生与社会保障部 | 2021-06-01 | — | — | CN | claimed |
| EP-3153530-B1 | COMPOSITE AND LAMINATE ARTICLES AND POLYMERIZABLE SYSTEMS FOR PRODUCING THE SAME | SIRRUS INC (US) | 2021-02-24 | — | — | EP | claimed |
| CN-112074497-A | Composition, process for its preparation and use of the composition as a water-repellent coating | 巴斯夫欧洲公司 | 2020-12-11 | — | — | CN | claimed |
| CN-111801306-A | Compositions containing methylene malonate monomers and polymers, their preparation and their use in flooring applications | 巴斯夫欧洲公司 | 2020-10-20 | — | — | CN | claimed |
| WO-2020039213-A1 | CHARCOAL-FREE CULTURE MEDIA FOR LEGIONELLA | Secretary of State for Health and Social Care (GB) | 2020-02-27 | — | — | WO | claimed |
| EP-2831125-B1 | METHODS FOR ACTIVATING POLYMERIZABLE COMPOSITIONS, POLYMERIZABLE SYSTEMS, AND PRODUCTS FORMED THEREBY | SIRRUS INC (US) | 2016-10-05 | — | — | EP | claimed |
| EP-2831124-B1 | COMPOSITE AND LAMINATE ARTICLES AND POLYMERIZABLE SYSTEMS FOR PRODUCING THE SAME | SIRRUS INC (US) | 2016-10-05 | — | — | EP | claimed |
| JP-10158547-A | — | — | None | — | — | JP | disclosed |
| EP-3805327-B1 | ANTIFOULING PAINT COMPOSITION | MITSUBISHI CHEM CORP (JP) | 2026-04-15 | — | — | EP | disclosed |
| JP-H10158547-A | ANTIFOULING COATING MATERIAL COMPOSITION | MITSUBISHI RAYON CO LTD | 1998-06-16 | — | — | JP | disclosed |
| EP-0754669-A1 | PROCESSES FOR PRODUCING ALPHA-HALO KETONES, ALPHA-HALOHYDRINS AND EPOXIDES | KANEKA CORPORATION (JP) | 1997-01-22 | — | — | EP | disclosed |
| US-4313850-A | METAL BIS(HALOCARBOXYLATE), OXYGENATED ORGANOTITANIUM, VANDIUM OR ZIRCONIUM COMPOUND AND AN ORGANOALUMIUM COMPOUND | STANDARD OIL COMPANY (INDIANA) (US) | 1982-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220033603-A1 | PROCESS AND COMPOSITION FOR THE PRODUCTION OF FLEXIBLE POLYURETHANE FOAM | PUF60, FUS, PCBP1 | CA4 1901/4885TSHR 4315/4885CASP1 3427/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.