SCHEMBL4588880

SCHEMBL4588880

CC(C)c1cc(C(C)C)c(S(=O)(=O)N[C@@H](Cc2cccc(C(=N)NO)c2)C(=O)O)c(C(C)C)c1

nearest known ligand 0.66

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
F10 P00742 6/20 0.66
PLG P00747 16/20 0.61
PLAU P00749 16/20 0.61
ST14 Q9Y5Y6 4/20 0.60
F2 P00734 3/20 0.60
HPN P05981 1/20 0.58
HGFAC Q04756 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6266784 0.89 F10 (0.82) F10PLGPLAUST14F2
SCHEMBL28534925 0.87 PLAU (0.73) F10PLGPLAUST14F2
SCHEMBL17700973 0.87 PLAU (0.73) F10PLGPLAUST14F2
N-(Ethoxycarbonyl)Piperazine SCHEMBL1809303 0.86 PLAU (0.67) F10PLGPLAUST14F2
N-(Ethoxycarbonyl)Piperazine SCHEMBL2875164 0.85 PLAU (0.65) F10PLGPLAUST14F2
SCHEMBL19922916 0.84 ST14 (0.84) F10PLGPLAUST14F2
SCHEMBL19922913 0.84 ST14 (0.84) F10PLGPLAUST14F2
Upamostat SCHEMBL12618906 0.82 PLAU (0.84) F10PLGPLAUST14F2
Upamostat SCHEMBL20674935 0.82 PLAU (0.84) F10PLGPLAUST14F2
Upamostat SCHEMBL30912299 0.82 PLAU (0.84) F10PLGPLAUST14F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080058346-A1 Crystalline Modifications of N-Alpha-(2,4,6-Triisopropylphenylsulfonyl)-3-Hydroxyamidino- (L)- Phenylalanine 4-Ethoxycarbonylpiperazide And/Or Salts Thereof WILEX AG (DE) 2008-03-06 US claimed
CN-117695284-B Treatment of coronavirus infection 红山生物医药有限公司 2025-06-17 CN disclosed
CN-117695284-A Treatment of coronavirus infection 红山生物医药有限公司 2024-03-15 CN disclosed
CN-115515560-B Treatment of coronavirus infection 红山生物医药有限公司 2023-12-15 CN disclosed
CN-115515560-A Treatment of coronavirus infection 红山生物医药有限公司 2022-12-23 CN disclosed