Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 20/20 | 0.60 |
| ▸ | HCRTR2 | O43614 | 15/20 | 0.60 |
| ▸ | TSPO | P30536 | 1/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.52 |
| ▸ | HTR2B | P41595 | 1/20 | 0.52 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1777248 | 1.00 | HCRTR1 (0.60) | HCRTR1HCRTR2TSPOOPRK1HTR2B | |
| SCHEMBL1777997 | 0.97 | HCRTR1 (0.64) | HCRTR1HCRTR2TSPOOPRK1HTR2B | |
| SCHEMBL1777324 | 0.94 | HCRTR1 (0.63) | HCRTR1HCRTR2TSPOOPRK1HTR2B | |
| SCHEMBL1777326 | 0.94 | HCRTR1 (0.63) | HCRTR1HCRTR2TSPOOPRK1HTR2B | |
| SCHEMBL1777780 | 0.93 | HCRTR1 (0.60) | HCRTR1HCRTR2TSPOOPRK1HTR2B | |
| SCHEMBL1779459 | 0.91 | HCRTR1 (0.58) | HCRTR1HCRTR2TSPOOPRK1HTR2B | |
| SCHEMBL1778949 | 0.91 | HCRTR1 (0.61) | HCRTR1HCRTR2TSPOOPRK1HTR2B | |
| SCHEMBL1777031 | 0.91 | HCRTR1 (0.59) | HCRTR1HCRTR2TSPOOPRK1HTR2B | |
| SCHEMBL1777454 | 0.90 | HCRTR1 (0.56) | HCRTR1HCRTR2TSPOOPRK1HTR2B | |
| SCHEMBL1777458 | 0.90 | HCRTR1 (0.56) | HCRTR1HCRTR2TSPOOPRK1HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7423052-B2 | Piperidine compounds for use as orexin receptor antagoinst | SMITHKLINE BEECHAM P.L.C. (GB) | 2008-09-09 | — | — | US | disclosed |