SCHEMBL4589362

SCHEMBL4589362

Cc1c(C(=O)NC2CCCC2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(C2CC2)cc1

nearest known ligand 0.86

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 12/20 0.86
CNR2 P34972 12/20 0.86

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14155463 0.99 CNR1 (0.88) CNR1CNR2
SCHEMBL14155481 0.96 CNR1 (0.79) CNR1CNR2
SCHEMBL276799 0.92 CNR1 (1.00) CNR1CNR2
SCHEMBL4250869 0.90 CNR1 (0.91) CNR1CNR2
SCHEMBL922625 0.89 CNR1 (0.90) CNR1CNR2
SCHEMBL22449360 0.89 CNR1 (0.89) CNR1CNR2
SCHEMBL14155455 0.86 CNR1 (0.82) CNR1CNR2
SCHEMBL14155469 0.85 CNR1 (0.84) CNR1CNR2
SCHEMBL14155483 0.85 CNR1 (0.81) CNR1CNR2
SCHEMBL4904806 0.85 CNR1 (0.86) CNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008075118-A1 NOVEL CB1 ANTAGONISTS AND THEIR PREPARATION RICHTER GEDEON NYRT. (HU) 2008-06-26 WO disclosed
WO-2008075118-A1 NOVEL CB1 ANTAGONISTS AND THEIR PREPARATION RICHTER GEDEON NYRT. (HU) 2008-06-26 WO disclosed