⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1972931 | 1.00 | — | — | |
| SCHEMBL1972865 | 1.00 | — | — | |
| SCHEMBL12248159 | 0.79 | — | — | |
| SCHEMBL9066293 | 0.78 | — | — | |
| SCHEMBL16732875 | 0.76 | — | — | |
| SCHEMBL10786853 | 0.76 | — | — | |
| SCHEMBL14282599 | 0.74 | TSHR (0.30) | — | |
| SCHEMBL14750423 | 0.74 | — | — | |
| SCHEMBL1503905 | 0.74 | TSHR (0.30) | — | |
| SCHEMBL1504090 | 0.74 | TSHR (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9616459-B1 | Polymeric coatings for fortification of visible, infrared, and laser optical devices | LOCKHEED MARTIN CORPORATION (US) | 2017-04-11 | — | — | US | claimed |
| CN-102351662-B | Preparation method of (S)-(+)-2-methoxylmethoxyl-1-propanol | CHANGZHOU HUAREN CHEMICAL CO LTD | 2014-02-05 | — | — | CN | claimed |
| CN-102351662-A | Preparation method of (S)-(+)-2-methoxylmethoxyl-1-propanol | CHANGZHOU HUAREN CHEMICAL CO LTD | 2012-02-15 | — | — | CN | claimed |
| CN-117330668-A | Method for separating and measuring isomer in (S) -2-methoxy-1-propanol | 常州合全药业有限公司 | 2024-01-02 | — | — | CN | disclosed |
| US-11802120-B2 | Fused cyclic urea derivatives as CRHR2 antagonist | RAQUALIA PHARMA INC. (JP) | 2023-10-31 | — | — | US | disclosed |
| CN-111868037-B | Fused cyclic urea derivatives as CRHR2 antagonists | 拉夸里亚创药株式会社 | 2023-10-13 | — | — | CN | disclosed |
| EP-3774739-B1 | FUSED CYCLIC UREA DERIVATIVES AS CRHR2 ANTAGONIST | RAQUALIA PHARMA INC (JP) | 2022-05-11 | — | — | EP | disclosed |
| US-20210078975-A1 | FUSED CYCLIC UREA DERIVATIVES AS CRHR2 ANTAGONIST | RAQUALIA PHARMA INC. (JP) | 2021-03-18 | — | — | US | disclosed |
| EP-3774739-A1 | FUSED CYCLIC UREA DERIVATIVES AS CRHR2 ANTAGONIST | RaQualia Pharma Inc. (JP) | 2021-02-17 | — | — | EP | disclosed |
| CN-111868037-A | Fused cyclic urea derivatives as CRHR2 antagonists | 拉夸里亚创药株式会社 | 2020-10-30 | — | — | CN | disclosed |
| WO-2019198692-A1 | FUSED CYCLIC UREA DERIVATIVES AS CRHR2 ANTAGONIST | RAQUALIA PHARMA INC. (JP) | 2019-10-17 | — | — | WO | disclosed |
| WO-2012033214-A1 | PEST CONTROLLING METHOD, COMPOSITION, ELECTROSTATIC SPRAY DEVICE AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-03-15 | — | — | WO | disclosed |
| CN-102351662-A | Preparation method of (S)-(+)-2-methoxylmethoxyl-1-propanol | CHANGZHOU HUAREN CHEMICAL CO LTD | 2012-02-15 | — | — | CN | disclosed |
| CN-102351662-A | Preparation method of (S)-(+)-2-methoxylmethoxyl-1-propanol | CHANGZHOU HUAREN CHEMICAL CO LTD | 2012-02-15 | — | — | CN | disclosed |
| CN-102351662-A | Preparation method of (S)-(+)-2-methoxylmethoxyl-1-propanol | CHANGZHOU HUAREN CHEMICAL CO LTD | 2012-02-15 | — | — | CN | disclosed |
| US-20110144343-A1 | PROCESS FOR PREPARING CANNABINOID RECEPTOR LIGANDS | ABBOTT LABORATORIES (US) | 2011-06-16 | — | — | US | disclosed |
| CN-1221505-C | Process for preparing alkanediol derivatives | IHARA CHEMICAL IND CO (JP) | 2005-10-05 | — | — | CN | disclosed |
| US-6720463-B1 | REDUCING AN ALKYLHYDROXYESTER WITH EASY TO HANDLE SODIUM BOROHYDRIDE; MAINTAINING OPTICAL ACTIVITY | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2004-04-13 | — | — | US | disclosed |
| CN-1336907-A | Process for the production of alkanediol derivatives | IHARA CHEMICAL IND CO (JP) | 2002-02-20 | — | — | CN | disclosed |
| EP-1146032-A1 | PROCESS FOR THE PRODUCTION OF ALKANEDIOL DERIVATIVES | IHARA CHEMICAL INDUSTRY Co., Ltd. (JP) | 2001-10-17 | — | — | EP | disclosed |