Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 7/20 | 0.49 |
| ▸ | SRC | P12931 | 5/20 | 0.49 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.43 |
| ▸ | FLT3 | P36888 | 1/20 | 0.43 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4588830 | 0.93 | FGFR1 (0.43) | FGFR1SRCNTRK1FLT3KCNA5 | |
| SCHEMBL4589926 | 0.88 | FGFR1 (0.49) | FGFR1SRCNTRK1FLT3KCNA5 | |
| SCHEMBL4590225 | 0.87 | KCNA5 (0.40) | KCNA5HRH3 | |
| SCHEMBL4590555 | 0.87 | KCNA5 (0.41) | KCNA5HRH3 | |
| SCHEMBL4590580 | 0.85 | FGFR1 (0.51) | FGFR1SRCNTRK1FLT3HRH3 | |
| SCHEMBL4589924 | 0.83 | FGFR1 (0.50) | FGFR1SRCNTRK1FLT3KCNA5 | |
| SCHEMBL4590150 | 0.83 | FGFR1 (0.54) | FGFR1SRCNTRK1FLT3HRH3 | |
| SCHEMBL4590536 | 0.80 | FGFR1 (0.46) | FGFR1SRCNTRK1FLT3HRH3 | |
| SCHEMBL4588823 | 0.78 | FGFR1 (0.45) | FGFR1SRCNTRK1FLT3KCNA5 | |
| SCHEMBL4590050 | 0.78 | FGFR1 (0.60) | FGFR1SRCHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008107322-A1 | INDOLE, BENZIMIDAZOLE OR BENZOTRIAZOLE DERIVATIVES INCLUDING A PIPERIDINE OR PIPERAZINE CORE AS ANTI-NEOPLASIC AGENTS OR CELL PROLIFERATION INHIBITORS | CEREP (FR) | 2008-09-12 | — | — | WO | claimed |