Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 18/20 | 0.48 |
| ▸ | KLK7 | P49862 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL470208 | 0.84 | TTK (0.66) | TTK | |
| SCHEMBL457295 | 0.79 | TTK (0.48) | TTK | |
| SCHEMBL456495 | 0.77 | TTK (0.53) | TTK | |
| SCHEMBL458605 | 0.77 | TTK (0.64) | TTK | |
| SCHEMBL459278 | 0.77 | TTK (0.65) | TTK | |
| SCHEMBL457244 | 0.77 | TTK (0.61) | TTK | |
| SCHEMBL470107 | 0.77 | TTK (0.66) | TTK | |
| SCHEMBL16295891 | 0.76 | TTK (0.74) | TTK | |
| SCHEMBL459511 | 0.76 | TTK (0.65) | TTK | |
| SCHEMBL458215 | 0.76 | TTK (0.60) | TTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2614063-A1 | SUBSTITUTED IMIDAZOPYRIDAZINES | Bayer Intellectual Property GmbH (DE) | 2013-07-17 | — | — | EP | disclosed |
| WO-2012032031-A1 | SUBSTITUTED IMIDAZOPYRIDAZINES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-03-15 | — | — | WO | disclosed |