Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6299448 | 0.80 | NPC1 (0.46) | ESR1ESR2CA1CA2 | |
| SCHEMBL9397850 | 0.77 | TSHR (0.50) | ESR1ESR2CA1CA2 | |
| SCHEMBL1204683 | 0.77 | TSHR (0.48) | CA1CA2 | |
| SCHEMBL9057542 | 0.77 | CA1 (0.38) | ESR1ESR2CA1CA2 | |
| SCHEMBL10883198 | 0.77 | ESR1 (0.46) | ESR1ESR2CA1CA2 | |
| SCHEMBL9908612 | 0.76 | ESR1 (0.58) | ESR1ESR2 | |
| SCHEMBL825609 | 0.75 | TSHR (0.48) | ESR1ESR2 | |
| SCHEMBL24507698 | 0.74 | TP53 (0.36) | ESR1ESR2CA1CA2 | |
| SCHEMBL5987914 | 0.74 | CA1 (0.38) | ESR1ESR2CA1CA2 | |
| SCHEMBL8846793 | 0.74 | TSHR (0.46) | CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9051419-B2 | Polymer | HALL RICHARD H (US) | 2015-06-09 | — | — | US | disclosed |
| US-20080171814-A1 | Polymer | HALL RICHARD H | 2008-07-17 | — | — | US | disclosed |