Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.38 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.38 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.37 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1061610 | 0.81 | ACP3 (0.47) | ACP3CNR2LMNAGAANFKB1 | |
| SCHEMBL7979002 | 0.80 | ACP3 (0.46) | ACP3CNR2LMNAGAANFKB1 | |
| SCHEMBL7472384 | 0.80 | ACP3 (0.46) | ACP3CNR2LMNAGAANFKB1 | |
| SCHEMBL8912757 | 0.80 | ACP3 (0.46) | ACP3CNR2LMNAGAANFKB1 | |
| SCHEMBL4778256 | 0.79 | ACP3 (0.45) | ACP3CNR2LMNAGAAALDH1A1 | |
| SCHEMBL7431712 | 0.79 | ACP3 (0.45) | ACP3CNR2LMNAGAANFKB1 | |
| SCHEMBL8887298 | 0.78 | ACP3 (0.42) | ACP3CNR2LMNAGAANFKB1 | |
| SCHEMBL7471669 | 0.77 | ACP3 (0.44) | ACP3CNR2LMNAGAANFKB1 | |
| Hydrochloric Acid SCHEMBL6559016 | 0.77 | ACP3 (0.44) | ACP3CNR2LMNAGAAALDH1A1 | |
| SCHEMBL28796970 | 0.76 | CNR2 (0.46) | ACP3CNR2LMNAGAANFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008100621-A2 | TETRAHYDRO-PYRAZOLO-PYRIDINE THIOETHER MODULATORS OF CATHEPSIN S | SUNESIS PHARMACEUTICALS, INC. (US) | 2008-08-21 | — | — | WO | claimed |
| EP-0014567-A1 | Processes for preparation of beta-lactam compounds | ELI LILLY AND COMPANY (US) | 1980-08-20 | — | — | EP | disclosed |